Jonathan P. Stoye

The Francis Crick Institute — United Kingdom

Immunology and Microbiology · Life Sciences

58h-index12.8kcitations171works2.72yr avg
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Research Topics

HIV Research and Treatment(60), Virus-based gene therapy research(38), Chromosomal and Genetic Variations(29), CRISPR and Genetic Engineering(29), Cytomegalovirus and herpesvirus research(22)

Publications171 total

Probing the molecular determinants of Ty1 retrotransposon restriction specificity in yeast
PLoS Genetics·2025· 1 citedOpen Access
Evolution of antiviral host defenses against a backdrop of endogenous retroelements
Science·2025· 5 citedOpen Access
2024 taxonomy update for the family Retroviridae
Archives of Virology·2025· 2 citedOpen Access
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export
PLoS Pathogens·2022· 48 citedOpen Access
Virus restriction: Repurposing an essential cellular function to defend against viruses
Current Biology·2022· 1 cited
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export
2022· 12 citedOpen Access
ICTV Virus Taxonomy Profile: Retroviridae 2021
Journal of General Virology·2021· 63 citedOpen Access
Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control
Nature Communications·2021· 22 citedOpen Access
Analysis of SAMHD1 Restriction by Flow Cytometry in Human Myeloid U937 Cells
Journal of Visualized Experiments·2021· 3 citedOpen Access
Analysis of SAMHD1 Restriction by Flow Cytometry in Human Myeloid U937 Cells
Journal of Visualized Experiments·2021Open Access
<i>Gv1</i>, a Zinc Finger Gene Controlling Endogenous MLV Expression
Molecular Biology and Evolution·2021· 12 citedOpen Access
Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses
PLoS Genetics·2020· 13 citedOpen Access
Antibody-induced internalisation of retroviral envelope glycoproteins is a signal initiation event
PLoS Pathogens·2020· 14 citedOpen Access
Structure of <i>Drosophila melanogaster</i> ARC1 reveals a repurposed molecule with characteristics of retroviral Gag
Science Advances·2020· 27 citedOpen Access
Repurposing of retroviral genes: when foe becomes self
TheScienceBreaker·2020Open Access
Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
Nature Communications·2019· 25 citedOpen Access
Duplication and divergence of the retrovirus restriction gene <i>Fv1</i> in <i>Mus caroli</i> mice allows protection from multiple retroviruses
2019Open Access
LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly
Genome Research·2019· 113 citedOpen Access
Positive selection in dNTPase SAMHD1 throughout mammalian evolution
Proceedings of the National Academy of Sciences·2019· 17 citedOpen Access
Structure of <i>D. melanogaster</i> ARC1 reveals a repurposed molecule with characteristics of retroviral Gag
2019· 2 citedOpen Access
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Frequent Co-authors

John M. Coffin(14), Melvyn W. Yap(9), Ian A. Taylor(6), Yasuhiro Takeuchi(5), George Kassiotis(5), David C. Goldstone(4), Harriet C. T. Groom(4), Sébastien Nisole(4), Paul Le Tissier(4), Kate N. Bishop(4), P.A. Walker(3), L.F. Haire(3), Greg J. Towers(3), Clive Patience(3), Robin A. Weiss(3), Michael Bock(3), George R. Young(3), Wayne N. Frankel(3), Evangelos Christodoulou(2), Michelle Webb(2)