Holger Willenbring

University of California, San Francisco — United States

Medicine · Health Sciences

35h-index8.1kcitations78works8.32yr avg
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Research Topics

Liver physiology and pathology(30), Pancreatic function and diabetes(19), Pluripotent Stem Cells Research(17), Organ Transplantation Techniques and Outcomes(11), Liver Disease Diagnosis and Treatment(9)

Publications78 total

Modeling Familial MASH by iPSC-Hepatocytes
2025Open Access
Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation
Science Translational Medicine·2025· 7 citedOpen Access
Proteomic Analysis of Perfusate from Normothermic Machine Perfusion of Human Livers Suggests Markers Associated with Organ Recovery
American Journal of Transplantation·2025
Identification of a robust promoter in mouse and human hepatocytes by in vivo biopanning of a barcoded AAV library
Molecular Therapy·2025· 5 citedOpen Access
AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion
Nature Biotechnology·2025· 23 citedOpen Access
Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers
2025· 1 citedOpen Access
Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system
Nature Communications·2024· 23 citedOpen Access
Human Hepatocytes Can Give Rise to Intrahepatic Cholangiocarcinomas
Gastroenterology·2024· 7 citedOpen Access
Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages
Nature Communications·2023· 33 citedOpen Access
Human iPSC‐Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System
Small·2023· 16 citedOpen Access
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Open MIND·2022
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Hepatology·2021Open Access
Aquaporin 9 induction in human iPSC‐derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency
Hepatology·2021· 23 citedOpen Access
Integrated Isogenic Human Induced Pluripotent Stem Cell–Based Liver and Heart Microphysiological Systems Predict Unsafe Drug–Drug Interaction
Frontiers in Pharmacology·2021· 52 citedOpen Access
Induced Pluripotent Stem Cell–derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile
Gastroenterology·2021· 29 citedOpen Access
Emerging cell therapy for biliary diseases
Science·2021· 9 citedOpen Access
Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction
2020· 13 citedOpen Access
iPSC-derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile
2020· 4 cited
Transcriptomic Traces of Adult Human Liver Progenitor Cells
Hepatology·2020· 3 cited
Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration
Cell stem cell·2019· 235 citedOpen Access
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Frequent Co-authors

Markus Grompe(10), Yann Malato(7), Milton J. Finegold(6), Raymond Ng(6), Garrett R. Roll(6), Milad Rezvani(5), Aras N. Mattis(5), Guisheng Song(5), William H. Fleming(4), Bernadette Y. Hsu(4), Jacquelyn J. Maher(4), Yassmine Akkari(3), Syed Naqvi(3), Dirk Grimm(3), Alexis S. Bailey(3), Amar Deep Sharma(3), K. John McLaughlin(3), Regina Español‐Suñer(3), Laure Dumont(3), Andrew Y. Lee(3)