Markus Grompe

Oregon Health & Science University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

96h-index40.8kcitations400works3.12yr avg
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Research Topics

DNA Repair Mechanisms(81), Liver physiology and pathology(78), Pancreatic function and diabetes(72), Metabolism and Genetic Disorders(59), CRISPR and Genetic Engineering(57)

Publications400 total

RAAVioli: A comprehensive approach to characterizing AAV vector integrations and rearrangements
Molecular Therapy Advances·2025Open Access
In vivo assessment of differential toxicity of cancer treatment drugs in Fanconi’s Anemia
2025Open Access
A porcine model of Fanconi anemia
PLoS ONE·2025Open Access
Cell networks in the mouse liver during partial hepatectomy
Stem Cell Reports·2025Open Access
One Shock, Not One Cure: Electroporation Reveals Disease-Specific Constraints in Hepatocyte Gene Editing Therapy
Biology·2025Open Access
Enhancing the potency of in vivo lentiviral vector mediated gene therapy to hepatocytes
Nature Communications·2025· 9 citedOpen Access
Hepatocyte senescence and persistent liver injury in Fanconi anemia
Haematologica·2025Open Access
Beyond Graft-Vs-Host Disease: The Role of Cellular Senescence in Persistent Liver Injury in Fanconi Anemia after HSCT
Transplantation and Cellular Therapy·2025
AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion
Nature Biotechnology·2025· 23 citedOpen Access
In vivo selection of hepatocytes
Hepatology·2024· 2 cited
AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model
2024· 1 citedOpen Access
Long‐term combination therapy with metformin and oxymetholone in a Fanconi anemia mouse model
Pediatric Blood & Cancer·2024· 2 cited
Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation
Hepatology·2023· 10 citedOpen Access
In vivo tracing of the Cytokeratin 14 lineages using self-cleaving guide RNAs and CRISPR/Cas9
Developmental Biology·2023Open Access
Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation
2023· 2 citedOpen Access
Long-term combination therapy with Metformin and Oxymetholone in a Fanconi Anemia mouse model
2023Open Access
Cell networks in the mouse liver during partial hepatectomy
2023Open Access
Strong ubiquitous micro-promoters for recombinant adeno-associated viral vectors
Molecular Therapy — Methods & Clinical Development·2023· 22 citedOpen Access
The DNA methylome of human vascular endothelium and its use in liquid biopsies
Med·2023· 18 cited
Supplementary Figures 1-4 from Deficiencies in the Fanconi Anemia DNA Damage Response Pathway Increase Sensitivity to HPV-Associated Head and Neck Cancer
2023Open Access
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Frequent Co-authors

Milton J. Finegold(17), Craig Dorrell(10), Muhsen Al-Dhalimy(9), Alan D. D’Andrea(6), Susan B. Olson(5), Eric Lagasse(4), Xin Wang(4), Toshiyasu Taniguchi(4), Jonathan Schug(4), Klaus H. Kaestner(4), Holger Willenbring(3), Mark P. Foster(3), Andrea Ballabio(3), Cynthia Timmers(3), Barbara Cox(3), Joshua Moss(3), Judith Magenheim(3), Kirsty L. Spalding(3), A. M. James Shapiro(3), Benjamin Gläser(3)