Jennifer Weiszmann

Amgen (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.9kcitations33works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Fibroblast Growth Factor Research(20), Kruppel-like factors research(18), Epigenetics and DNA Methylation(14), Receptor Mechanisms and Signaling(7), Peroxisome Proliferator-Activated Receptors(6)

Publications33 total

FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
eLife·2019· 44 citedOpen Access
Author response: FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
2019Open Access
Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions
Journal of Biological Chemistry·2018· 34 citedOpen Access
A systematic dissection of sequence elements determining β-Klotho and FGF interaction and signaling
Scientific Reports·2018· 28 citedOpen Access
Impact of antibody subclass and disulfide isoform differences on the biological activity of CD200R and βklotho agonist antibodies
Biochemical and Biophysical Research Communications·2017· 11 cited
A Novel Fc-FGF21 With Improved Resistance to Proteolysis, Increased Affinity Toward β-Klotho, and Enhanced Efficacy in Mice and Cynomolgus Monkeys
Endocrinology·2017· 103 citedOpen Access
Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action
EBioMedicine·2016· 55 citedOpen Access
Fibroblast Growth Factor Receptor 4 (FGFR4) Deficiency Improves Insulin Resistance and Glucose Metabolism under Diet-induced Obesity Conditions
Journal of Biological Chemistry·2014· 62 citedOpen Access
FGF21 Can Be Mimicked In Vitro and In Vivo by a Novel Anti-FGFR1c/β-Klotho Bispecific Protein
PLoS ONE·2013· 56 citedOpen Access
A Novel Approach to Improve the Function of FGF21
BioDrugs·2013· 20 cited
Dual actions of figrowth factor 19 on lipid metabolism
2013
Discovery of INT131: A selective PPARγ modulator that enhances insulin sensitivity
Bioorganic & Medicinal Chemistry·2012· 42 citedOpen Access
Dual actions of fibroblast growth factor 19 on lipid metabolism
Journal of Lipid Research·2012· 63 citedOpen Access
Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the βKlotho/FGFR1c Receptor Complex
Science Translational Medicine·2012· 211 cited
Characterization of a FGF19 Variant with Altered Receptor Specificity Revealed a Central Role for FGFR1c in the Regulation of Glucose Metabolism
PLoS ONE·2012· 45 citedOpen Access
A Unique FGF23 with the Ability to Activate FGFR Signaling through Both αKlotho and βKlotho
Journal of Molecular Biology·2012· 18 cited
The FGFR D3 Domain Determines Receptor Selectivity For Fibroblast Growth Factor 21
Journal of Molecular Biology·2011· 17 cited
Mutational analysis of G-protein coupled receptor – FFA2
Biochemical and Biophysical Research Communications·2011· 21 cited
Allosteric rescuing of loss‐of‐function FFAR2 mutations
FEBS Letters·2010· 11 cited
Separating mitogenic and metabolic activities of fibroblast growth factor 19 (FGF19)
Proceedings of the National Academy of Sciences·2010· 98 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Yang Li(32), Hongfei Ge(16), Jamila Gupte(16), Xinle Wu(14), Bryan D. Lemon(10), Richard Lindberg(10), Hélène Baribault(9), Jinlong Chen(6), Hui Tian(6), Jennitte Stevens(6), Jonitha Gardner(6), Minghan Wang(5), Zhulun Wang(5), Murielle M. Véniant(5), Zhulun Wang(5), Nessa Hawkins(5), Jun Zhang(5), Michelle Lindström(4), Jackie Sheng(4), Steven Vonderfecht(4)