Shankar Sadasivan

Thomas Jefferson University — United States

Neuroscience · Life Sciences

14h-index938citations20works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(4), Autophagy in Disease and Therapy(4), Metabolomics and Mass Spectrometry Studies(4), Neuroinflammation and Neurodegeneration Mechanisms(4), Alzheimer's disease research and treatments(3)

Publications20 total

Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus
PLoS ONE·2021· 10 citedOpen Access
Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo
Brain·2018· 149 citedOpen Access
Synergistic effects of influenza and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can be eliminated by the use of influenza therapeutics: experimental evidence for the multi-hit hypothesis
npj Parkinson s Disease·2017· 61 citedOpen Access
Induction of Microglia Activation after Infection with the Non-Neurotropic A/CA/04/2009 H1N1 Influenza Virus
PLoS ONE·2015· 129 citedOpen Access
Necrosis, Apoptosis and Autophagy in Acute Brain Injury: The Utilities of Biomarkers
2014
p75 Regulates Purkinje Cell Firing by Modulating SK Channel Activity through Rac1
Journal of Biological Chemistry·2014· 20 citedOpen Access
Correction: Methylphenidate Exposure Induces Dopamine Neuron Loss and Activation of Microglia in the Basal Ganglia of Mice
PLoS ONE·2012· 21 citedOpen Access
Methylphenidate Exposure Induces Dopamine Neuron Loss and Activation of Microglia in the Basal Ganglia of Mice
PLoS ONE·2012· 102 citedOpen Access
Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype
BMC Neuroscience·2010· 56 citedOpen Access
Methods in Systems Biology of Experimental Methamphetamine Drug Abuse
Methods in molecular biology·2010· 7 cited
P1.006 Neurochemical and neuroplastic changes in chronic methyphenidate administered brains
Parkinsonism & Related Disorders·2009
Methods in Drug Abuse Neuroproteomics: Methamphetamine Psychoproteome
Methods in molecular biology·2009· 6 cited
Neuroproteomics and systems biology‐based discovery of protein biomarkers for traumatic brain injury and clinical validation
PROTEOMICS - CLINICAL APPLICATIONS·2008· 70 cited
Changes in autophagy proteins in a rat model of controlled cortical impact induced brain injury
Biochemical and Biophysical Research Communications·2008· 51 cited
Psychoproteomic Analysis of Rat Cortex Following Acute Methamphetamine Exposure
Journal of Proteome Research·2008· 42 cited
Psychiatric research: psychoproteomics, degradomics and systems biology
Expert Review of Proteomics·2008· 36 cited
Role of Autophagy in Neuronal Injury Models of the Central Nervous System
University of Florida Digital Collections (University of Florida)·2008
Calpain-Mediated Collapsin Response Mediator Protein-1, -2, And -4 Proteolysis after Neurotoxic And Traumatic Brain Injury
Journal of Neurotrauma·2007· 114 cited
γ‐Hydroxybutyrate (GHB), γ‐Butyrolactone (GBL), and 1,4‐Butanediol (1,4‐BD) Reduce the Volume of Cerebral Infarction in Rodent Transient Middle Cerebral Artery Occlusion
Annals of the New York Academy of Sciences·2006· 17 cited
Amino acid starvation induced autophagic cell death in PC-12 cells: Evidence for activation of caspase-3 but not calpain-1
APOPTOSIS·2006· 47 cited

Frequent Co-authors

Kevin Wang(10), Richard J. Smeyne(8), Firas Kobeissy(7), Ronald L. Hayes(5), Zuo‐Feng Zhang(5), Brooks B. Pond(3), Amar K. Pani(3), Stephen F. Larner(3), Mark S. Gold(3), Yun Jiao(2), Stacey Schultz‐Cherry(2), Zhiqun Zhang(2), Andrew K. Ottens(2), Chunxu Qu(2), William A. Dunn(2), Е. А. Козина(1), Yuchen Dou(1), Zhijun Ma(1), Haiyan Tan(1), Kiran Kodali(1)