Illhwan Cho

Yonsei University — South Korea

Medicine · Health Sciences

8h-index238citations24works7.12yr avg
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Research Topics

Alzheimer's disease research and treatments(21), Cholinesterase and Neurodegenerative Diseases(13), Computational Drug Discovery Methods(7), Neuroscience and Neuropharmacology Research(5), Supramolecular Self-Assembly in Materials(5)

Publications24 total

Synthesis of 3-desoxycollinoketone B and its ability to reduce Alzheimer-associated misfolded proteins
Nature Communications·2026Open Access
IK‐5f targets amyloid aggregates and alleviates cognitive deficits in the 5XFAD Alzheimer mouse model
Alzheimer s & Dementia·2025Open Access
AS‐YFluor, a Novel Fluorescent Imaging Agent Detecting Aβ42 Oligomers in Blood for Alzheimer Diagnosis
Alzheimer s & Dementia·2025Open Access
A new chemical entity dissociates amyloid‐β aggregation and alleviates Alzheimer‐induced cognitive decline
Alzheimer s & Dementia·2025Open Access
Tau Repeats Promote Amyloid‐β Fibril Disassembly <i>in Vitro</i>
Alzheimer s & Dementia·2025Open Access
Synthesis of 3-dehydroxy-5-epi-collinoketone and its cognitive benefits by reducing aggregates of amyloid-β and tau
2025· 2 citedOpen Access
Tau Repeats Disassemble Amyloid-β Fibrils <i>In Vitro</i> by Interacting with KLVFFA and GGVVIA Domains
ACS Chemical Neuroscience·2025
Aryloxypropanolamine mitigates Alzheimer‐like phenotype by directly removing amyloid aggregates
Alzheimer s & Dementia·2024Open Access
PFTAIRE peptide degrading cyclin Y and ameliorating cognitive deficits in mouse models of Alzheimer’s Disease
Alzheimer s & Dementia·2024Open Access
The mapping of active sites of amyloid‐targeting compounds through the utilization of immobilized fragments of amyloid hexamers
Alzheimer s & Dementia·2024Open Access
Modulation of Amyloid and Tau Aggregation to Alleviate Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease
ACS Pharmacology & Translational Science·2024· 1 citedOpen Access
Chemically Driven Clearance of Amyloid Aggregates by Polyfunctionalized Furo[2,3-<i>b</i>:4,5-<i>b</i>′]dipyridine–Chalcone Hybrids to Ameliorate Memory in an Alzheimer Mouse Model
Molecular Pharmaceutics·2024· 1 cited
Early onset diagnosis in Alzheimer’s disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid
Nature Communications·2024· 88 citedOpen Access
Benzo[<i>d</i>]imidazole-pyrrolo[1,2-<i>a</i>]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice
ACS Chemical Neuroscience·2023· 9 cited
4-Acyl-3,4-dihydropyrrolo[1,2-<i>a</i>]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble Aβ Aggregates
ACS Chemical Neuroscience·2023· 6 cited
Pioneering the Early Diagnosis of Alzheimer’s Disease: Aβ Oligomers-Sensing Probe for Cerebrospinal Fluid Analysis in Patients
2023Open Access
Glycosylated and Succinylated Macrocyclic Lactones with Amyloid-β-Aggregation-Regulating Activity from a Marine Bacillus sp.
Marine Drugs·2023· 3 citedOpen Access
Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β3-42 peptide
Scientific Reports·2023· 8 citedOpen Access
Immobilized Amyloid Hexamer Fragments to Map Active Sites of Amyloid-Targeting Chemicals
ACS Chemical Neuroscience·2022· 12 citedOpen Access
Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models
Alzheimer s Research & Therapy·2022· 10 citedOpen Access
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Frequent Co-authors

Young Soo Kim(17), Soljee Yoon(16), Hye Yun Kim(14), Kyeonghwan Kim(10), Jisu Shin(8), Minhae Cha(8), Ikyon Kim(8), Suhyun Ye(8), InWook Park(7), Songmin Lee(7), Dong-Hee Lee(6), Keunwan Park(5), In Wook Park(4), Heewon Shin(4), Seung‐Hoon Yang(3), Sejin Lee(3), Seungyeop Baek(3), Hee Yang Lee(3), Sunhee Lee(3), Jusung An(2)