Jianyang Zeng

Westlake University — China

Computer Science · Physical Sciences

36h-index6.3kcitations147works3.42yr avg
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Research Topics

Computational Drug Discovery Methods(47), Protein Structure and Dynamics(41), RNA and protein synthesis mechanisms(29), Bioinformatics and Genomic Networks(24), RNA Research and Splicing(16)

Publications147 total

Detection of Somatic Point Mutations Directly from Spatial Transcriptomics Enables in vivo Spatiotemporal Lineage Tracing
2026Open Access
ProMeta: A meta-learning framework for robust disease diagnosis and prediction from plasma proteomics
2026Open Access
Network Pharmacology and Drug Repurposing
2025
High-accuracy protein complex structure modeling based on sequence-derived structure complementarity
Nature Communications·2025· 2 citedOpen Access
STARNet enables spatially resolved inference of gene regulatory networks from spatial multi-omics data
2025· 1 citedOpen Access
Single-cell polygenic risk scores dissect cellular and molecular heterogeneity of complex human diseases
Nature Biotechnology·2025· 5 citedOpen Access
High-accuracy protein complex structure modeling based on sequence-derived structure complementarity
2025· 1 citedOpen Access
Des-γ-carboxy Prothrombin in hepatocellular carcinoma post-operative recurrence risk evaluation
Communications Medicine·2025· 1 citedOpen Access
20P Molecular characteristics of rare gynecological mesonephric-like adenocarcinoma: Analysis from a comprehensive whole-exome and mRNA sequencing
ESMO Open·2025Open Access
Modeling gene interactions in polygenic prediction via geometric deep learning
Genome Research·2024· 5 citedOpen Access
DrugRepPT: a deep pretraining and fine-tuning framework for drug repositioning based on drug’s expression perturbation and treatment effectiveness
Bioinformatics·2024· 1 citedOpen Access
Revolutionizing biomolecular structure determination with artificial intelligence
National Science Review·2024· 5 citedOpen Access
From Static to Dynamic Structures: Improving Binding Affinity Prediction with Graph‐Based Deep Learning
Advanced Science·2024· 20 citedOpen Access
Analyzing Large-Scale Single-Cell RNA-Seq Data Using Coreset
IEEE/ACM Transactions on Computational Biology and Bioinformatics·2024
Benchmarking compound activity prediction for real-world drug discovery applications
Communications Chemistry·2024· 13 citedOpen Access
19P Molecular characteristics of rare gynecological mesonephric(like) adenocarcinoma: A comprehensive analysis using whole exon sequencing and mRNA sequencing
ESMO Open·2024Open Access
How has the AI boom impacted algorithmic biology?
Cell Systems·2024Open Access
Deconvolution of polygenic risk score in single cells unravels cellular and molecular heterogeneity of complex human diseases
2024· 3 citedOpen Access
A probabilistic knowledge graph for target identification
PLoS Computational Biology·2024· 3 citedOpen Access
Antisense oligonucleotide depletion of <i>CCDC146</i> is a broad-spectrum therapeutic strategy for ALS
2024· 4 citedOpen Access
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Frequent Co-authors

Dan Zhao(17), Fangping Wan(16), Shuya Li(14), Tao Jiang(10), Hailin Hu(9), Tingzhong Tian(9), Hantao Shu(7), Jingtian Zhou(6), Ligong Chen(6), Lixiang Hong(6), Sai Zhang(6), Yipin Lei(6), Han Li(6), Yunan Luo(5), Yuanpeng Xiong(5), Jinglin Yang(3), Jian Peng(3), An Xiao(3), Haipeng Gong(3), Shao Li(3)