Emad H. M. Hassanein

Al-Azhar University — Egypt

Medicine · Health Sciences

30h-index2.1kcitations85works4.22yr avg
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Research Topics

Chemotherapy-induced organ toxicity mitigation(31), Genomics, phytochemicals, and oxidative stress(27), Drug-Induced Hepatotoxicity and Protection(15), Heavy Metal Exposure and Toxicity(8), Acute Lymphoblastic Leukemia research(8)

Publications85 total

Renoprotective effect of diosmin against chlorpyrifos-induced kidney injury is mediated by the regulation of TLR4/HMGB1/NF-κB, PPAR-γ/SIRT1, and Bax/Bcl2 signals
Journal of Molecular Histology·2025
Nifuroxazide attenuates bisphenol A–induced male reproductive toxicity by modulating oxidative stress, inflammation, and Nrf2/HO-1 and necroptosis pathways
Tissue and Cell·2025
Candesartan preserves aortic structure and function in cisplatin-treated rats by upregulating SIRT1/Nrf2/HO-1 signaling and suppressing oxidative stress, TLR-4/NF-κB signaling, and necroptosis
Frontiers in Pharmacology·2025Open Access
S-Carboxymethylcysteine Mitigates Cyclophosphamide-Induced Hepatotoxicity by Modulating TLR-4/NF-κB Signaling and Redox Homeostasis
Bratislavské lekárske listy/Bratislava medical journal·2025Open Access
Retraction notice to “Combined apocynin and carvedilol protect against cadmium-induced testicular damage via modulation of inflammatory response and redox-sensitive pathways” [Life Sci. 311 (2022) 121152]
Life Sciences·2025Open Access
The Involvement of RIPK‐3/Caspase‐8 Inhibition and Nrf2/HO‐1 Upregulation in the Protective Effect of Umbelliferone Against Chlorpyrifos‐Induced Pulmonary Toxicity
Journal of Biochemical and Molecular Toxicology·2025
BS29 Ambroxol attenuates cyclophosphamide cardiotoxicity by suppressing NF-κB/NLRP3 inflammasome axis and oxidative stress, and upregulating NRF2/HO-1 signalling
2025Open Access
Upregulation of Nrf2/HO-1 signaling and farnesoid X receptor and attenuation of oxidative stress and inflammation mediate the protective effect of sitagliptin against diabetic nephropathy in rats
International Immunopharmacology·2025· 1 citedOpen Access
Involvement of IL‐6/JAK/STAT3/SOCS3, SIRT1, and Cytoglobin Signaling in Diacerein Protective Effect against Intestinal Injury Induced by Methotrexate
Journal of Biochemical and Molecular Toxicology·2025· 1 cited
Exploring the potentials of chitosan as a promising carrier for methotrexate for beating cancer
International Journal of Biological Macromolecules·2025· 1 cited
Impact of lisinopril on cisplatin-induced inflammation, oxidative stress, apoptosis, and impaired steroidogenesis in rat testis: involvement of Nrf2/Keap1/HO-1 and PPARγ signaling
Naunyn-Schmiedeberg s Archives of Pharmacology·2025· 1 cited
Targeting TLR4/NF-κB signaling, oxidative stress, and apoptosis by farnesol mitigates cadmium-induced testicular toxicity in rats
Tissue and Cell·2025· 3 cited
Morin Mitigates 5-Fluorouracil-Induced Nephrotoxicity by Activating Nrf2/HO-1 and FXR, and Suppressing ERK/VCAM-1 and NF-κB Pathways
International Immunopharmacology·2025· 4 cited
Chitosan/Carbon Nanocomposites in Drug Delivery and Cardiovascular Diseases
Smart nanomaterials technology·2025· 1 cited
Diallyl disulfide prevents cadmium-induced testicular injury by attenuating oxidative stress, apoptosis, and TLR-4/NF-κB and JAK1/STAT3 signaling and upregulating SIRT1 in rats
Journal of Trace Elements in Medicine and Biology·2024· 4 cited
Diallyl Disulfide Mitigates Cadmium Hepatotoxicity by Attenuating Oxidative Stress and TLR-4/NF-κB Signaling and Upregulating PPARγ
Frontiers in Bioscience-Landmark·2024· 3 citedOpen Access
Oxidative Stress, Inflammation, and Altered Lymphocyte E-NTPDase Are Implicated in Acute Dyslipidemia in Rats: Protective Role of Arbutin
Pharmaceuticals·2024· 4 citedOpen Access
Neuroprotective effect of diosmin against chlorpyrifos-induced brain intoxication was mediated by regulating PPAR-γ and NF-κB/AP-1 signals
Food and Chemical Toxicology·2024· 12 cited
Molecular mechanisms underlying methotrexate-induced intestinal injury and protective strategies
Naunyn-Schmiedeberg s Archives of Pharmacology·2024· 12 citedOpen Access
BS39 The angiotensin II receptor blocker candesartan attenuates cisplatin cardiovascular toxicity by suppressing TLR4/NF-κB signalling and oxidative stress
2024· 1 citedOpen Access
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Frequent Co-authors

Fares E.M. Ali(19), Ahmed M. Sayed(13), Ayman M. Mahmoud(13), Omnia A. M. Abd El‐Ghafar(10), Abdel‐Gawad S. Shalkami(7), Wafaa R. Mohamed(7), Hanan S. Althagafy(7), Ramadan A.M. Hemeida(6), Tarek Hamdy Abd‐Elhamid(6), Eman K. Rashwan(6), Marwa M. Khalaf(5), Islam M. Ibrahim(5), Esraa K. Abd‐alhameed(5), Basel A. Abdel‐Wahab(5), Amany Refaat Mahmoud(4), Zainab Omar(4), Marwa A. Ahmed(4), Emadeldin M. Kamel(4), Zuhair M. Mohammedsaleh(4), Reem S. Alruhaimi(4)