Lionel Berthoin

Arsenal Biosciences (United States) — United States

Medicine · Health Sciences

1h-index2citations5works0.02yr avg
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Research Topics

CAR-T cell therapy research(3), CRISPR and Genetic Engineering(2), Cancer Genomics and Diagnostics(1), Single-cell and spatial transcriptomics(1), Immune cells in cancer(1)

Publications5 total

DINOcell: learning generalizable perturbation effects through self-distillation
2025Open Access
259 Discovery of synthetic signaling pathway receptors that increase the potency of CAR-T cells through optimized STAT activity
Regular and Young Investigator Award Abstracts·2023Open Access
Abstract 4073: Tunable STAT activation by synthetic pathway activators (SPAs) increases engineered T-cell potency and persistence
Cancer Research·2023
332 CRISPR/Cas9-based integration of a large and modular cassette into a safe harbor site to improve CAR T cell therapy efficacy and safety
Regular and Young Investigator Award Abstracts·2022· 2 citedOpen Access
Abstract 1701: Single-cell multi-omic profiling and clonal tracing of the human gynecological tumor microenvironment
Cancer Research·2022

Frequent Co-authors

David DeTomaso(4), Aaron Cooper(4), W. Nicholas Haining(4), Brendan Galvin(3), Sofia Kyriazopoulou Panagiotopoulou(3), Manching Ku(3), Anzhi Yao(3), Ashley Cass(3), Azalea Ong(3), Meng Hiot Lim(3), Natalie Bezman(3), Rene Sit(2), Shan Sabri(2), Matt Drever(2), Grace Zheng(2), Thomas J. Gardner(2), Beatriz Millare(2), Suchismita Mohanty(2), Jeremy Chen(2), Alma Gomez(2)