Aaron Cooper

Memorial Sloan Kettering Cancer Center — United States

Medicine · Health Sciences

24h-index2.5kcitations91works0.82yr avg
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Research Topics

CAR-T cell therapy research(22), CRISPR and Genetic Engineering(19), Virus-based gene therapy research(15), Sarcoma Diagnosis and Treatment(11), Biochemical Analysis and Sensing Techniques(8)

Publications91 total

DINOcell: learning generalizable perturbation effects through self-distillation
2025Open Access
245 Synthetic pathway activators (SPA) enhance CAR-T activity against solid tumors by reducing T cell exhaustion and increasing functional persistence in preclinical studies
Regular and Young Investigator Award Abstracts·2025Open Access
1125 gx1: virtual target identification for overcoming T cell exhaustion
Regular and Young Investigator Award Abstracts·2025Open Access
256 Preclinical development of AB-3028, a logic-gated engineered CAR T cell product intended for the treatment of metastatic castration-resistant prostate cancer (mCRPC)
Regular and Young Investigator Award Abstracts·2025Open Access
258 Programmable circuit T cells encoding multiplexed shRNAs and logic-gates for mCRPC
Regular and Young Investigator Award Abstracts·2025Open Access
303 AB-3028: Dual-targeting sequential AND logic gated CAR T cell for potential mCRPC therapeutic
Regular and Young Investigator Award Abstracts·2025Open Access
MA01.04 Neoadjuvant PD-(L)1 Blockade in Combination With Chemotherapy for Borderline Resectable and Unresectable Stage III Non-Small Cell Lung Cancer
Journal of Thoracic Oncology·2025
P1.11.55 Identifying Patients Cured From Metastatic Non-Small Cell Lung Cancer (mNSCLC) With Anti-PD-(L)1 Therapy
Journal of Thoracic Oncology·2025
Abstract 6395: Synthetic pathway activators enhance CAR-T functional persistence and prevent T cell exhaustion
Cancer Research·2025· 1 cited
Author response: High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025Open Access
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
eLife·2025· 1 citedOpen Access
Author response: High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025Open Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025· 1 citedOpen Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024· 2 citedOpen Access
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
eLife·2024· 10 citedOpen Access
Author response: High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024Open Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024Open Access
P2.11A.12 Machine Learning-Based Clinicogenomic Prediction of Response to PD-(L)1 Inhibition in KRAS Altered Non-Small Cell Lung Cancer
Journal of Thoracic Oncology·2024Open Access
Abstract B080: AB-1015, an Integrated Circuit T (ICT) cell therapy containing an ALPG/MSLN logic gate and FAS/PTPN2 shRNA-miR, for the treatment of ovarian cancer
Cancer Research·2024
259 Discovery of synthetic signaling pathway receptors that increase the potency of CAR-T cells through optimized STAT activity
Regular and Young Investigator Award Abstracts·2023Open Access
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Frequent Co-authors

Donald B. Kohn(23), Roger P. Hollis(13), Michael L. Kaufman(10), Zulema Romero(9), Fabrizia Urbinati(9), Georgia R. Lill(8), Joshua S. Bloom(8), Nathan B. Lubock(8), Sriram Kosuri(7), Megan D. Hoban(6), Shantha Senadheera(6), Sabine Geiger(6), Eric M. Jones(6), Dianne Lumaquin(5), Xiaoyan Wang(5), Beatriz Campo-Fernández(5), Elizabeth R. Lawlor(5), Satiro De Oliveira(5), José Costa(5), Fabio Candotti(4)