Sriram Kosuri

University of California, Los Angeles — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index8.7kcitations83works4.12yr avg
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Research Topics

RNA and protein synthesis mechanisms(31), CRISPR and Genetic Engineering(19), Bacterial Genetics and Biotechnology(17), Advanced biosensing and bioanalysis techniques(12), Biochemical Analysis and Sensing Techniques(11)

Publications83 total

OpenADMET: Embracing the Avoid-Ome to Transform Drug Discovery
Preprints.org·2025Open Access
Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease
2025· 1 citedOpen Access
Covalent Degraders of Immune Regulatory Transcription Factors IRF8 and IRF5
2025· 1 citedOpen Access
Author response: High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025Open Access
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
eLife·2025· 1 citedOpen Access
A Massively Parallel Reporter Assay Library to Screen Short Synthetic Promoters in Mammalian Cells (Abstract ID: 159301)
Journal of Pharmacology and Experimental Therapeutics·2025
Author response: High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025Open Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025· 1 citedOpen Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024· 2 citedOpen Access
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
eLife·2024· 10 citedOpen Access
Author response: High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024Open Access
A massively parallel reporter assay library to screen short synthetic promoters in mammalian cells
Nature Communications·2024· 15 citedOpen Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024Open Access
Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes
Nature Communications·2024· 27 citedOpen Access
Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation
2023· 14 citedOpen Access
Reviewer #1 (Public Review): Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation
2023Open Access
Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation
2023· 7 citedOpen Access
Reviewer #3 (Public Review): Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation
2023Open Access
Reviewer #2 (Public Review): Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation
2023Open Access
Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants
Cell Genomics·2023· 38 citedOpen Access
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Frequent Co-authors

Nathan B. Lubock(15), George M. Church(12), Kimberly D. Insigne(12), Eric M. Jones(10), Jessica E. Davis(10), Joshua S. Bloom(9), Guillaume Urtecho(6), Leonid Kruglyak(6), Hwangbeom Kim(5), Marcia S. Brinck(5), Daniel B. Goodman(4), Drew Endy(4), Angus M. Sidore(4), Rockie Chong(4), Arielle D. Tripp(4), Aaron Cooper(4), Jay Shendure(4), Tracey W. Chan(4), Jeffrey Wang(3), Daniel Cancilla(3)