Françoise Carlotti

Leiden University Medical Center — Netherlands

Medicine · Health Sciences

32h-index4.6kcitations110works3.92yr avg
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Research Topics

Pancreatic function and diabetes(74), Diabetes and associated disorders(41), Diabetes Management and Research(22), Metabolism, Diabetes, and Cancer(12), Virus-based gene therapy research(8)

Publications110 total

Iron deficiency induces maturation-dependent loss of pancreatic β-cells
Nature Communications·2026Open Access
Transient ER stress cell-autonomously promotes beta cell cycling in mice
Diabetologia·2026Open Access
Beta hydroxybutyrate alters beta cell identity and function in human islets
2025
Latent plasticity of the human pancreas across development, health, and disease
2025· 1 citedOpen Access
BMP5 signalling in beta cells and the impact on insulin secretion in the context of type 2 diabetes
Diabetologia·2025Open Access
Iron deficiency induces maturation-dependent loss of pancreatic β-cells
2025Open Access
14-1: IN VITRO TREATMENT-UPREGULATED NKX6.1 EXPRESSION IN HUMAN ISLETS IMPROVES ISLET FUNCTION POST TRANSPLANTATION IN MOUSE.
Transplantation·2025
Methylprednisolone Protects Human Pancreatic Beta Cells From Inflammation-induced Damage
Transplantation Direct·2025Open Access
Clinically compliant enrichment of human pluripotent stem cell–derived islets
Science Translational Medicine·2025· 2 cited
Effects of Neurogenin 3 Induction on Endocrine Differentiation and Delamination in Adult Human Pancreatic Ductal Organoids
Transplant International·2025Open Access
miRNA-642a-3p protects β cells from glucolipotoxicity
Molecular Therapy — Nucleic Acids·2025· 1 citedOpen Access
Cell type-specific eQTL detection from single-cell RNA-seq reveals post-transcriptional regulatory mechanisms in human islets
2025Open Access
Subcutaneous Implantation of Open Microwell Islet Delivery Devices in Pigs
Surgical Innovation·2024· 1 citedOpen Access
Stem cell islet replacement in type 1 diabetes: From “shelf” to “self”
Cell stem cell·2024· 2 cited
Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages
Cell·2024· 20 citedOpen Access
Enhanced BMP Signaling Alters Human β‐Cell Identity and Function
Advanced Biology·2024· 3 citedOpen Access
ER stress relief drives ß-cell proliferation
2024Open Access
Single-cell transcriptomics reveals a role for pancreatic duct cells as potential mediators of inflammation in diabetes mellitus
Frontiers in Immunology·2024· 8 citedOpen Access
Pancreatic β-Cell Identity Change through the Lens of Single-Cell Omics Research
International Journal of Molecular Sciences·2024· 9 citedOpen Access
Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system
Cytotherapy·2024· 7 citedOpen Access
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Frequent Co-authors

Eelco J.P. de Koning(30), Rob C. Hoeben(18), Arnaud Zaldumbide(14), Marten A. Engelse(12), Ton J. Rabelink(11), Maaike Hanegraaf(7), Johanne H. Ellenbroek(6), Arno R. van der Slik(5), Bart O. Roep(5), Matthias S. Roost(5), Christine L. Mummery(5), Natascha de Graaf(5), Philippe Pognonec(4), H. Siebe Spijker(4), Susana M. Chuva de Sousa Lopes(4), H.A.M. Töns(4), Aart A. van Apeldoorn(4), Liesbeth van Iperen(4), Sofia Thomaidou(4), Nathalie Gröen(3)