Sofia Thomaidou

Leiden University Medical Center — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index811citations17works3.52yr avg
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Research Topics

Diabetes and associated disorders(14), Pancreatic function and diabetes(11), Diet, Metabolism, and Disease(5), Immune Cell Function and Interaction(4), Diabetes Management and Research(3)

Publications17 total

Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
EBioMedicine·2025· 8 citedOpen Access
Ribosome profiling shows variable sensitivity to detect open reading frames for conventional and different types of cryptic T cell antigens
Molecular Therapy — Methods & Clinical Development·2024Open Access
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
2024· 3 citedOpen Access
Pharmacological Inhibition of Tyrosine Protein-Kinase 2 Reduces Islet Inflammation and Delays Type 1 Diabetes Onset in Mice
SSRN Electronic Journal·2024· 3 citedOpen Access
IFNɣ but not IFNα increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity
Diabetologia·2023· 16 citedOpen Access
EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion
Molecular Metabolism·2023· 35 citedOpen Access
25-OR: ADA Presidents' Select Abstract: Preclinical Evaluation of TYK2 Inhibitors in Type 1 Diabetes
Diabetes·2023· 1 cited
Presence of immunogenic alternatively spliced insulin gene product in human pancreatic delta cells
Diabetologia·2023· 8 citedOpen Access
ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation
Frontiers in Endocrinology·2022· 18 citedOpen Access
Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells
Science Advances·2022· 37 citedOpen Access
Long RNA Sequencing and Ribosome Profiling of Inflamed β-Cells Reveal an Extensive Translatome Landscape
Diabetes·2021· 19 citedOpen Access
Long-RNA Sequencing and Ribosome Profiling of Inflamed Beta-Cells Reveal an Extensive Translatome Landscape
2021Open Access
Long-RNA Sequencing and Ribosome Profiling of Inflamed Beta-Cells Reveal an Extensive Translatome Landscape
2021Open Access
Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)
Nature Reviews Endocrinology·2020· 572 citedOpen Access
MUSEUMS, DIGITAL TRANSFORMATION AND MOOCS. AN ITALIAN CASE STUDY
EDULEARN proceedings·2020
β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1
Diabetes·2020· 44 citedOpen Access
Islet stress, degradation and autoimmunity
Diabetes Obesity and Metabolism·2018· 47 citedOpen Access

Frequent Co-authors

Arnaud Zaldumbide(16), Bart O. Roep(8), Arno R. van der Slik(7), Françoise Carlotti(7), Rob C. Hoeben(6), Ângela Castela(6), Décio L. Eizirik(6), Maria Inês Alvelos(5), Stéphane Demine(5), Piero Marchetti(5), Alexandra Coomans de Brachène(5), Lorella Marselli(4), Amadeo Muñoz García(4), Olivia Ballew(4), Chih‐Chun Lee(4), Jyoti Rana(4), Staci A. Weaver(4), Garrick Chang(4), Kara S. Orr(4), Donalyn Scheuner(4)