Ângela Castela

Université Libre de Bruxelles — Belgium

Medicine · Health Sciences

18h-index1.3kcitations43works15.52yr avg
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Research Topics

Pancreatic function and diabetes(14), Diabetes and associated disorders(14), Sexual function and dysfunction studies(10), Hormonal and reproductive studies(8), Urinary Bladder and Prostate Research(5)

Publications43 total

Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
EBioMedicine·2025· 8 citedOpen Access
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
2024· 3 citedOpen Access
Interferons are key cytokines acting on pancreatic islets in type 1 diabetes
Diabetologia·2024· 48 citedOpen Access
Pharmacological Inhibition of Tyrosine Protein-Kinase 2 Reduces Islet Inflammation and Delays Type 1 Diabetes Onset in Mice
SSRN Electronic Journal·2024· 3 citedOpen Access
Interferons are the key cytokines acting on pancreatic islets in type 1 diabetes
2023· 2 citedOpen Access
25-OR: ADA Presidents' Select Abstract: Preclinical Evaluation of TYK2 Inhibitors in Type 1 Diabetes
Diabetes·2023· 1 cited
ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation
Frontiers in Endocrinology·2022· 18 citedOpen Access
Exercise as a non-pharmacological intervention to protect pancreatic beta cells in individuals with type 1 and type 2 diabetes
Diabetologia·2022· 37 citedOpen Access
Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells
Science Advances·2022· 37 citedOpen Access
A functional genomic approach to identify reference genes for human pancreatic beta cell real-time quantitative RT-PCR analysis
Islets·2021· 16 citedOpen Access
A functional genomic approach to identify reference genes for human pancreatic beta cell real-time quantitative RT-PCR analysis
2021· 1 citedOpen Access
Endogenous mitochondrial double‐stranded RNA is not an activator of the type I interferon response in human pancreatic beta cells
Autoimmunity Highlights·2021· 8 citedOpen Access
The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells
Life Science Alliance·2020· 19 citedOpen Access
Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta‐cell protection in type 1 diabetes
Diabetes Obesity and Metabolism·2020· 38 citedOpen Access
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells
Nature Communications·2020· 132 citedOpen Access
Author response for "Pre‐clinical evaluation of <scp>TYK2</scp> inhibitors for human beta cell protection in type 1 diabetes"
2020
Pre-clinical evaluation of TYK2 inhibitors for beta cell protection in type 1 diabetes
2019
Xanthohumol and 8-prenylnaringenin reduce type 2 diabetes–associated oxidative stress by downregulating galectin-3
Porto Biomedical Journal·2018· 27 citedOpen Access
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction
EBioMedicine·2018· 181 citedOpen Access
Erectile dysfunction and diabetes – evaluation of molecular alterations induced by oxidative stress
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)·2017
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Frequent Co-authors

Décio L. Eizirik(17), Pedro Vendeira(16), Piero Marchetti(15), Alexandra Coomans de Brachène(14), Carla Costa(14), Lorella Marselli(13), Maria Inês Alvelos(11), Raquel Soares(11), Pedro Gomes(10), R Virag(9), Máikel L. Colli(7), Carmella Evans‐Molina(7), Anne Op De Beeck(6), Florian Szymczak(6), Sofia Thomaidou(6), Arnaud Zaldumbide(6), Sandra Marín‐Cañas(5), Stéphane Demine(5), Noel G. Morgan(4), Sarah J. Richardson(4)