Erich R. Kuechler

University of British Columbia — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index399citations24works0.02yr avg
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Research Topics

RNA Research and Splicing(8), Protein Structure and Dynamics(7), Spectroscopy and Quantum Chemical Studies(7), Heat shock proteins research(6), Enzyme Structure and Function(5)

Publications24 total

Analysis of protein levels and solubility in distinct brain regions reveals several elements of the protein homeostasis network that are impacted by aging
2024Open Access
Shift of the insoluble content of the proteome in the aging mouse brain
Proceedings of the National Academy of Sciences·2023· 18 citedOpen Access
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
Cell Reports·2023· 38 citedOpen Access
Comparison of Biomolecular Condensate Localization and Protein Phase Separation Predictors
Biomolecules·2023· 10 citedOpen Access
Shift of the insoluble content of the proteome in aging mouse brain
2022· 1 citedOpen Access
Pulse labeling reveals the tail end of protein folding by proteome profiling
Cell Reports·2022· 16 citedOpen Access
GraPES: The Granule Protein Enrichment Server for prediction of biological condensate constituents
Nucleic Acids Research·2022· 17 citedOpen Access
NAD Depletion Mediates Cytotoxicity in Human Neurons With Autophagy Deficiency
SSRN Electronic Journal·2022· 2 citedOpen Access
Stress Granule Protein Features Allow for Accurate Prediction of Biological Condensate Localization with GraPES
The FASEB Journal·2021
Pulse labeling reveals the tail end of protein folding by proteome profiling
2021Open Access
Protein feature analysis of heat shock induced ubiquitination sites reveals preferential modification site localization
Journal of Proteomics·2021· 10 cited
Pulse Labeling Reveals the Tail End of Protein Folding by Proteome Profiling
SSRN Electronic Journal·2021Open Access
Protein–Protein Interactions Mediated by Intrinsically Disordered Protein Regions Are Enriched in Missense Mutations
Biomolecules·2020· 35 citedOpen Access
Proteomic analysis reveals the direct recruitment of intrinsically disordered regions to stress granules in <i>S. cerevisiae</i>
Journal of Cell Science·2020· 28 citedOpen Access
Distinct Features of Stress Granule Proteins Predict Localization in Membraneless Organelles
Journal of Molecular Biology·2020· 76 citedOpen Access
Proteomic analysis reveals the recruitment of intrinsically disordered regions to stress granules
2019· 2 citedOpen Access
A Multidimensional B-Spline Correction for Accurate Modeling Sugar Puckering in QM/MM Simulations
Journal of Chemical Theory and Computation·2017· 16 citedOpen Access
VR-SCOSMO: A smooth conductor-like screening model with charge-dependent radii for modeling chemical reactions
The Journal of Chemical Physics·2016· 5 citedOpen Access
Charge-dependent many-body exchange and dispersion interactions in combined QM/MM simulations
The Journal of Chemical Physics·2015· 27 citedOpen Access
Charge-dependent non-bonded interaction methods for use in quantum mechanical modeling of condensed phase reactions
University of Minnesota Digital Conservancy (University of Minnesota)·2015Open Access
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Frequent Co-authors

Thibault Mayor(13), Jörg Gsponer(9), Darrin M. York(7), Joerg Gsponer(7), Mang Zhu(7), Timothy J. Giese(4), Thakshila Dissanayake(3), Tai‐Sung Lee(3), Brian K. Radak(3), Cristen Molzahn(3), Neil R. Cashman(3), Aly Karsan(3), Philipp F. Lange(3), Nikolay Stoynov(3), Haoyuan Chen(2), George M. Giambaşu(2), Ming Huang(2), Maria T. Panteva(2), Congxin Sun(2), Elena Seranova(2)