Philipp F. Lange

University of British Columbia — Canada

Chemistry · Physical Sciences

23h-index2.6kcitations96works1.22yr avg
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Research Topics

Advanced Proteomics Techniques and Applications(35), Acute Lymphoblastic Leukemia research(24), Peptidase Inhibition and Analysis(19), Glycosylation and Glycoproteins Research(18), Protease and Inhibitor Mechanisms(8)

Publications96 total

Poster Session II - A219 CHARACTERIZATION OF METHYLATION MODIFICATIONS OF HUMAN COLONOID MONOLAYERS ESTABLISHED AS <i>IN VITRO</i> CHRONIC DAMAGE MODEL
Journal of the Canadian Association of Gastroenterology·2026Open Access
mTOR Inhibition in the Management of Recurrent Metastatic Solid Pseudopapillary Tumor of the Pancreas
Pediatric Blood & Cancer·2025
ProteoForge: An Imputation-Aware Framework for Differential Proteoform Discovery in Bottom-Up Proteomics
2025
Molecular rewiring of human induced pluripotent stem cell-derived cardiomyocytes during metabolic maturation
2025Open Access
Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe
EMBO Molecular Medicine·2025Open Access
1649 The Proteomic Landscape of Pediatric Osteosarcomas
Laboratory Investigation·2025
Molecular and metabolomic characterization of hiPSC-derived cardiac fibroblasts transitioning to myofibroblasts
Frontiers in Cell and Developmental Biology·2024· 2 citedOpen Access
Granzyme B cleaves tenascin-C to release its C-terminal domain in rheumatoid arthritis
JCI Insight·2024· 5 citedOpen Access
Developing a soft micropatterned substrate to enhance maturation of human induced pluripotent stem cell-derived cardiomyocytes
Acta Biomaterialia·2024· 5 citedOpen Access
Abstract PR003: Canada’s path towards proteome guided therapies and advanced molecular pathology in pediatric precision oncology
Cancer Research·2024· 1 cited
Proteomics and personalized patient-derived xenograft models identify treatment opportunities for a progressive malignancy within a clinically actionable timeframe and change care
2024Open Access
Statistical Testing for Protein Equivalence Identifies Core Functional Modules Conserved across 360 Cancer Cell Lines and Presents a General Approach to Investigating Biological Systems
Journal of Proteome Research·2024· 3 citedOpen Access
Abstract 937: Prioritizing treatment targets for an adolescent with metastatic processive malignancy using proteomics and personalized xenograft models within an actionable timeframe
Cancer Research·2024
The Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia
Leukemia·2024· 2 citedOpen Access
Analysis of protein levels and solubility in distinct brain regions reveals several elements of the protein homeostasis network that are impacted by aging
2024Open Access
Targetable lesions and proteomes predict therapy sensitivity through disease evolution in pediatric acute lymphoblastic leukemia
Nature Communications·2023· 10 citedOpen Access
Shift of the insoluble content of the proteome in the aging mouse brain
Proceedings of the National Academy of Sciences·2023· 18 citedOpen Access
Positional proteomics: is the technology ready to study clinical cohorts?
Expert Review of Proteomics·2023· 2 cited
Molecular and metabolomic characterization of hiPSC-derived cardiac fibroblasts transitioning to myofibroblasts
2023Open Access
Adaptation of the Th-MYCN Mouse Model of Neuroblastoma for Evaluation of Disseminated Disease
International Journal of Molecular Sciences·2023· 2 citedOpen Access
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Frequent Co-authors

Christopher M. Overall(15), Anuli C. Uzozie(12), Pitter F. Huesgen(10), Lorenz Nierves(9), Christopher A. Maxwell(8), Amanda Lorentzian(7), Ulrich auf dem Keller(6), Enes K. Ergin(6), Janice Tsui(6), Caroline L. Bellac(5), Reinhild Kappelhoff(5), Chinten James Lim(5), Gregor S. D. Reid(5), Ulrich Eckhard(4), Georgina S. Butler(4), Verena Goebeler(4), Amanda E. Starr(4), Zhengcheng He(4), Nina Rolf(4), Siyuan Chen(4)