David D. Christ

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

29h-index3.0kcitations77works0.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(18), Drug Transport and Resistance Mechanisms(13), Receptor Mechanisms and Signaling(9), Chemical Synthesis and Analysis(7), Computational Drug Discovery Methods(6)

Publications76 total

Toxicokinetics and Drug Disposition
Toxicologic Pathology·2018
6.14 AEVI-001 Pharmacokinetics in Pediatric Patients With Attention-Deficit/Hyperactivity Disorder (ADHD): Open-Label Single Ascending Dose Study
Journal of the American Academy of Child & Adolescent Psychiatry·2017
The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Francisella tularensis SCHU S4 Infection in BALB/c Mice and Cynomolgus Macaques
Antimicrobial Agents and Chemotherapy·2017· 16 citedOpen Access
129 A phase 1 drug-drug interaction study of CTX-4430 assessing CYP3A4 induction
Journal of Cystic Fibrosis·2015Open Access
Toxicokinetics and Drug Disposition
Toxicologic Pathology·2013
Wiley Series on Technologies for the Pharmaceutical Industry
2012· 1 cited
Front Matter
2012
Index
2012Open Access
Faculty Opinions recommendation of High-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2012
Anaphylactic shock after sensitization to gelatin
British Journal of Anaesthesia·2011· 13 citedOpen Access
Faculty Opinions recommendation of A zone classification system for risk assessment of idiosyncratic drug toxicity using daily dose and covalent binding.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2009
Faculty Opinions recommendation of Shape induced inhibition of phagocytosis of polymer particles.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2009
Potent, Orally Bioavailable Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery of<i>N</i>,<i>N</i>-Diethyl-4-(5-hydroxyspiro[chromene-2,4′-piperidine]-4-yl)benzamide (ADL5859)
Journal of Medicinal Chemistry·2008· 89 citedOpen Access
Faculty Opinions recommendation of Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2008
Faculty Opinions recommendation of Identification and design of peptides as a new drug delivery system for the brain.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2008
Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE): Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1′ substituents
Bioorganic & Medicinal Chemistry Letters·2008· 56 citedOpen Access
Potent, exceptionally selective, orally bioavailable inhibitors of TNF-α Converting Enzyme (TACE): Novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1′ substituents
Bioorganic & Medicinal Chemistry Letters·2008· 46 citedOpen Access
α,β-Cyclic-β-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE)
Bioorganic & Medicinal Chemistry Letters·2008· 14 citedOpen Access
CCDC 670062: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
α,β-Cyclic-β-benzamido hydroxamic acids: Novel templates for the design, synthesis, and evaluation of selective inhibitors of TNF-α converting enzyme (TACE)
Bioorganic & Medicinal Chemistry Letters·2007· 36 citedOpen Access
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Frequent Co-authors

Maryanne Covington(16), Mingxin Qian(15), Robert Newton(15), Rui‐Qin Liu(14), Carl P. Decicco(14), James J.‐W. Duan(12), James M. Trzăskos(11), Ruth R. Wexler(8), Krishna Vaddi(8), J G Kenna(7), Zelda R. Wasserman(7), L R Pohl(5), Zhonghui Lu(5), Ronald L. Magolda(5), Hiroaki Satoh(4), Abdul Mutlib(4), Karl D. Hardman(4), Robert J. Cherney(4), Dayton T. Meyer(4), Chu‐Biao Xue(4)