An Zwijsen

KU Leuven — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index6.2kcitations115works2.02yr avg
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Research Topics

TGF-β signaling in diseases(35), Congenital heart defects research(24), Pluripotent Stem Cells Research(17), Renal and related cancers(16), Developmental Biology and Gene Regulation(11)

Publications115 total

FOXO1 unlocks SMAD function to drive mechano-induced endothelial-to-mesenchymal transition
2026Open Access
Loss of endothelial ZEB2 in mice attenuates steatosis early during metabolic dysfunction-associated steatotic liver disease
Scientific Reports·2025Open Access
Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and Atherosclerosis
2024· 2 citedOpen Access
Smad1/5 is acetylated in the dorsal aortae of the mouse embryo before the onset of blood flow, driving early arterial gene expression
Cardiovascular Research·2024· 3 citedOpen Access
Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis in juvenile bone
Communications Biology·2024· 5 citedOpen Access
Functional and topological analysis of PSENEN, the fourth subunit of the γ-secretase complex
Journal of Biological Chemistry·2023· 6 citedOpen Access
Functional and topological analysis of PSENEN, the fourth subunit of the γ-secretase complex
2023Open Access
Withdrawal: Functional and topological analysis of Pen-2, the fourth subunit of the γ-secretase complex
Journal of Biological Chemistry·2023Open Access
The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency
Nature Communications·2023· 26 citedOpen Access
Efficient generation of ETX embryoids that recapitulate the entire window of murine egg cylinder development
Science Advances·2023· 19 citedOpen Access
Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis during long bone growth
2023· 1 citedOpen Access
The development of the amnion in mice and other amniotes
Philosophical Transactions of the Royal Society B Biological Sciences·2022· 28 citedOpen Access
The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency
2022· 4 citedOpen Access
Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo
The EMBO Journal·2022· 19 citedOpen Access
Table S2 from The development of the amnion in mice and other amniotes
Figshare·2022Open Access
Table S4 from The development of the amnion in mice and other amniotes
Figshare·2022Open Access
Table S3 from The development of the amnion in mice and other amniotes
Figshare·2022Open Access
Combined deletion of PR-domain containing 16 (Prdm16) in cardiomyocyte and non-cardiomyocyte lineages results in spontaneous early-onset lethality and progressive left ventricular dysfunction in mice
European Heart Journal·2021
The BMP Pathway in Blood Vessel and Lymphatic Vessel Biology
International Journal of Molecular Sciences·2021· 20 citedOpen Access
Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function
Circulation Research·2021· 33 citedOpen Access
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Frequent Co-authors

Danny Huylebroeck(22), Lieve Umans(18), Yuji Mishina(5), Paulo N. G. Pereira(5), Annick Francis(5), Richard R. Behringer(4), Christine L. Mummery(4), Mariya P. Dobreva(4), Vesa Kaartinen(4), Bart De Strooper(3), Hua Chang(3), Martin M. Matzuk(3), Tom Van de Putte(3), Iván M. Moya(3), Karen Beets(3), Marie‐José Goumans(3), Luk Cox(3), Andrea Conidi(3), Liesbeth Vermeire(3), Ramya Rajagopal(3)