Indira H. Shrivastava

National Institute for Occupational Safety and Health — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index7.4kcitations82works0.02yr avg
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Research Topics

Ion channel regulation and function(20), Neuroscience and Neuropharmacology Research(12), Protein Structure and Dynamics(11), Ferroptosis and cancer prognosis(11), Lipid Membrane Structure and Behavior(10)

Publications80 total

Formation of protein adducts with Hydroperoxy-PE electrophilic cleavage products during ferroptosis
Redox Biology·2023· 25 citedOpen Access
The suppressing role of nitric oxide in the ferroptotic cell death signal transduction
Biophysical Journal·2022· 1 cited
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death
Redox Biology·2022· 42 citedOpen Access
NO● Represses the Oxygenation of Arachidonoyl PE by 15LOX/PEBP1: Mechanism and Role in Ferroptosis
International Journal of Molecular Sciences·2021· 40 citedOpen Access
Redox Epiphospholipidome in Programmed Cell Death Signaling: Catalytic Mechanisms and Regulation
Frontiers in Endocrinology·2021· 32 citedOpen Access
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
Nature Chemical Biology·2021· 302 citedOpen Access
New insight into the significance of KLF4 PARylation in genome stability, carcinogenesis, and therapy
EMBO Molecular Medicine·2020· 15 citedOpen Access
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis
Redox Biology·2020· 128 citedOpen Access
Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane
Toxins·2020· 34 citedOpen Access
PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells
Proceedings of the National Academy of Sciences·2020· 113 citedOpen Access
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death
Nature Chemical Biology·2020· 592 citedOpen Access
Allostery as Structure‐Encoded Collective Dynamics
2020· 1 cited
Naja mossambica mossambica Cobra Cardiotoxin Targets Mitochondria to Disrupt Mitochondrial Membrane Structure and Function
Toxins·2019· 41 citedOpen Access
Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members
Journal of Chemical Information and Modeling·2019· 44 citedOpen Access
Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE
Journal of the American Chemical Society·2018· 81 citedOpen Access
Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction?
Free Radical Biology and Medicine·2018· 342 cited
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium
Journal of Clinical Investigation·2018· 234 citedOpen Access
PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals
Cell·2017· 892 citedOpen Access
“Only a Life Lived for Others Is Worth Living”: Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions
Antioxidants and Redox Signaling·2017· 35 citedOpen Access
Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis
EBioMedicine·2016· 78 citedOpen Access
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Frequent Co-authors

İvet Bahar(23), Valerian E. Kagan(15), Hülya Bayır(14), Yulia Y. Tyurina(13), Mark S.P. Sansom(12), Vladimir A. Tyurin(11), Tamil S. Anthonymuthu(10), Alexandr A. Kapralov(9), Haider H. Dar(9), Karolina Mikulska‐Ruminska(9), Andrew A. Amoscato(7), Sally E. Wenzel(6), Gaowei Mao(6), Andrew P. VanDemark(6), Shridhar R. Gadre(6), Simon C. Watkins(5), Claudette M. St. Croix(5), Joel S. Greenberger(5), Ruben K. Dagda(4), Joel C. Rosenbaum(4)