Guido Silvestri

University of North Carolina at Chapel Hill — United States

Immunology and Microbiology · Life Sciences

80h-index26.8kcitations417works4.62yr avg
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Research Topics

HIV Research and Treatment(301), Immune Cell Function and Interaction(155), T-cell and B-cell Immunology(84), Cytomegalovirus and herpesvirus research(78), HIV/AIDS Research and Interventions(76)

Publications416 total

Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
Immunity·2025· 2 citedOpen Access
Identifying correlates of viral rebound timing and viral control in SHIV-infected infant macaques after ART interruption
Science Translational Medicine·2025· 1 cited
HIV Env trimers elicit NHP apex cross-neutralizing antibodies mimicking human bNAbs
2025· 1 citedOpen Access
HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
Science Immunology·2025· 5 citedOpen Access
Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques
npj Vaccines·2025Open Access
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
Science Translational Medicine·2025· 7 citedOpen Access
BCL-2 Inhibition via Venetoclax at ART Initiation Induces Long-Term Reduction of the Intact SIV Reservoir
2025· 1 citedOpen Access
Correction for Mavigner et al., “Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques”
UNC Libraries·2025Open Access
Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques
UNC Libraries·2025· 1 citedOpen Access
Correction for Mavigner et al., “Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques”
UNC Libraries·2025Open Access
Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
UNC Libraries·2025Open Access
Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques
Communications Medicine·2025Open Access
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer
Immunity·2025· 3 cited
Safety, pharmacokinetics, and biological activity of CD4-mimetic BNM-III-170 in SHIV-infected rhesus macaques
Journal of Virology·2025· 1 citedOpen Access
Diverse priming outcomes under conditions of very rare precursor B cells
Immunity·2025· 8 citedOpen Access
TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size
2025Open Access
Immune-mediated strategies to solving the HIV reservoir problem
Nature reviews. Immunology·2025· 9 cited
SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection
Translational Psychiatry·2025Open Access
Vaccination with mRNA-encoded membrane-bound HIV Envelope trimer induces neutralizing antibodies in animal models
2025· 3 citedOpen Access
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption
Nature Immunology·2025Open Access
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Frequent Co-authors

Mirko Paiardini(16), Steven E. Bosinger(13), Jacob D. Estes(12), Daniel C. Douek(11), Jason M. Brenchley(9), Thomas H. Vanderford(9), Donald L. Sodora(8), Jeffrey D. Lifson(8), Shane Crotty(8), Ann Chahroudi(8), Diane G. Carnathan(7), Cristian Apetrei(7), James G. Else(6), Dennis R. Burton(6), Shari N. Gordon(6), Ivona Pandrea(6), Silvija I. Staprans(5), Mark B. Feinberg(5), Barbara Cervasi(5), Nichole R. Klatt(5)