Dennis R. Burton

Scripps Research Institute — United States

Immunology and Microbiology · Life Sciences

172h-index99.6kcitations796works7.42yr avg
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Research Topics

HIV Research and Treatment(414), Monoclonal and Polyclonal Antibodies Research(348), Immune Cell Function and Interaction(176), Glycosylation and Glycoproteins Research(130), T-cell and B-cell Immunology(100)

Publications796 total

Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
Immunity·2025· 2 citedOpen Access
Structure-guided design of native-like HIV Env Single Chain Trimers for enhanced stability, immunogenicity, and versatile vaccine delivery
2025Open Access
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques
2025· 1 citedOpen Access
Engineering HIV antibodies with enhanced breadth and potency of neutralization through multistate affinity maturation
2025Open Access
Directed evolution of a stem-helix–targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity
2025Open Access
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2
The Journal of Experimental Medicine·2025· 2 citedOpen Access
HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
Science Immunology·2025· 5 citedOpen Access
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Cell Reports·2025· 7 citedOpen Access
Rapid acquisition of HIV-1 neutralization breadth in a rhesus V2 apex germline antibody mouse model after a single bolus immunization
2025Open Access
Microfluidics combined with electron microscopy for rapid and high-throughput mapping of antibody–viral glycoprotein complexes
Nature Biomedical Engineering·2025· 6 citedOpen Access
Combining a rhesus cytomegalovirus/SIV vaccine with a neutralizing antibody to protect against SIV challenges in rhesus macaques
Frontiers in Microbiology·2025· 1 citedOpen Access
Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development
2025· 8 citedOpen Access
Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope
Cell Reports·2025· 3 citedOpen Access
Combining a rhesus cytomegalovirus/SIV vaccine with neutralizing antibody to protect against SIV challenge in rhesus macaques
2025Open Access
Longitudinal analysis of drift in the circulating human antibody repertoire over four years
2025Open Access
The saponin monophosphoryl lipid A nanoparticle adjuvant induces dose-dependent HIV vaccine responses in nonhuman primates
Journal of Clinical Investigation·2025· 6 citedOpen Access
Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques
PLoS Pathogens·2025· 1 citedOpen Access
Modulation of antigen delivery and lymph node activation in nonhuman primates by saponin adjuvant saponin/monophosphoryl lipid A nanoparticle
PNAS Nexus·2024· 9 citedOpen Access
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire
PLoS Pathogens·2024· 4 citedOpen Access
Modulation of antigen delivery and lymph node activation in non-human primates by saponin adjuvant SMNP
2024· 3 citedOpen Access
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Frequent Co-authors

Ian A. Wilson(16), John P. Moore(10), Pascal Poignard(9), Jean‐Philippe Julien(8), Wayne C. Koff(8), Paul W.H.I. Parren(8), Laura M. Walker(6), Devin Sok(6), Peter D. Kwong(6), Ann J. Hessell(6), Andrew B. Ward(6), Erica Ollmann Saphire(5), Michael B. Zwick(5), Robyn L. Stanfield(5), Hermann Katinger(5), Richard T. Wyatt(5), William R. Schief(5), Terri Wrin(4), Melissa Simek(4), Joseph G. Jardine(4)