Robyn L. Stanfield

Scripps Research Institute — United States

Medicine · Health Sciences

63h-index19.5kcitations226works4.92yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(97), Glycosylation and Glycoproteins Research(66), HIV Research and Treatment(65), Immune Cell Function and Interaction(25), T-cell and B-cell Immunology(16)

Publications225 total

Rational design of next-generation filovirus vaccines combining glycoprotein stabilization and nanoparticle display with glycan modification
Nature Communications·2025Open Access
Using phage display for rational engineering of a higher-affinity humanized 3’ phosphohistidine-specific antibody
Communications Chemistry·2025Open Access
The conserved bridging domain on HCV E1E2 glycoprotein complex is targeted by neutralizing antibodies from diverse lineages
2025· 1 citedOpen Access
Structural and genetic signatures of two classes of HCV E2 neutralizing face antibodies from non-human primates immunized with a recombinant E1E2
2025Open Access
Origin of immunoglobulins and T cell receptors: A candidate gene for invasion by the RAG transposon
Science Advances·2025· 3 citedOpen Access
Abstract Th0018: Rational Engineering of δ-Plasmin-Antibody Complexes as Direct-Acting Thrombolytics
Arteriosclerosis Thrombosis and Vascular Biology·2025
Rational design of next-generation filovirus vaccines through glycoprotein stabilization, nanoparticle display, and glycan modification
2025· 2 citedOpen Access
Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains
Journal of Medicinal Chemistry·2024· 3 cited
Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus
Nature Communications·2024· 20 citedOpen Access
Cladophorol-A is an inhibitor of cyclic GMP-AMP synthase
Bioorganic & Medicinal Chemistry Letters·2024· 1 cited
Small Molecule Kinetic Stabilizers Reduce Amyloidogenicity of Free Light Chain Proteins of Diverse Sequences in λ Light Chain Amyloidosis
Blood·2024· 1 citedOpen Access
Using phage display for rational engineering of a higher affinity humanized 3’phosphohistidine-specific antibody
2024· 1 citedOpen Access
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire
PLoS Pathogens·2024· 4 citedOpen Access
Mispacking of the <scp>F87</scp> sidechain drives aggregation‐promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer
Protein Science·2024· 1 citedOpen Access
A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers
2024· 4 citedOpen Access
Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer
2024Open Access
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins
Science Translational Medicine·2024· 51 citedOpen Access
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire
2024· 2 citedOpen Access
Probing the dissociation and reassembly pathway of an amyloidogenic homotetramer
Biophysical Journal·2024Open Access
Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant
Journal of the American Chemical Society·2023· 12 citedOpen Access
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Frequent Co-authors

Ian A. Wilson(45), Dennis R. Burton(22), Andrew B. Ward(12), John P. Moore(9), Albert Cupo(7), Rogier W. Sanders(7), Michael B. Zwick(5), Pauline M. Rudd(5), Raymond A. Dwek(5), Jean‐Philippe Julien(5), Devin Sok(5), Hermann Katinger(5), Leopold Kong(5), Robert Pejchal(4), Pascal Poignard(4), Gabriel Ozorowski(4), Fernando Garcés(4), Yuanzi Hua(4), Martin F. Flajnik(4), Erica Ollmann Saphire(3)