Deborah Young

University of Auckland — New Zealand

Neuroscience · Life Sciences

47h-index13.3kcitations126works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(26), RNA Interference and Gene Delivery(13), Neuroinflammation and Neurodegeneration Mechanisms(12), Nerve injury and regeneration(11), Virus-based gene therapy research(11)

Publications126 total

Heat shock factor <scp>HSF1</scp> regulates <scp>BDNF</scp> gene promoters upon acute stress in the hippocampus, together with <scp>pCREB</scp>
Journal of Neurochemistry·2022· 15 citedOpen Access
AAV Targeting of Glial Cell Types in the Central and Peripheral Nervous System and Relevance to Human Gene Therapy
Frontiers in Molecular Neuroscience·2021· 101 citedOpen Access
Platelet-Reactive Antibodies in Patients after Ischaemic Stroke—An Epiphenomenon or a Natural Protective Mechanism
International Journal of Molecular Sciences·2020· 2 citedOpen Access
The NMDA Receptor Antibody Paradox: A Possible Approach to Developing Immunotherapies Targeting the NMDA Receptor
Frontiers in Neurology·2020· 12 citedOpen Access
Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury
Experimental Neurology·2020· 37 cited
Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury
2019· 5 citedOpen Access
Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury
Gene Therapy·2019· 87 citedOpen Access
Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics
Science Advances·2019· 59 citedOpen Access
Targeting Transgene and RNA Interference-Based Gene Silencing Sequences to Astrocytes Using Viral Vector-Mediated Approaches
Elsevier eBooks·2018
Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis
Platelets·2017· 22 citedOpen Access
Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis
Figshare·2017Open Access
Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer
Molecular Therapy — Methods & Clinical Development·2016· 23 citedOpen Access
Gene Therapy-Based Modeling of Neurodegenerative Disorders: Huntington’s Disease
Methods in molecular biology·2015· 4 cited
An infant not moving her leg
The American Journal of Emergency Medicine·2015· 1 cited
Gene Therapy for Huntington’s Disease
Neuromethods·2015
A novel bicistronic sensor vector for detecting caspase-3 activation
Journal of Pharmacological and Toxicological Methods·2014· 9 cited
Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy
Gene Therapy·2014· 35 citedOpen Access
An Immunological Approach to Increase the Brain’s Resilience to Insults
ISRN Neuroscience·2014· 1 citedOpen Access
AAV-Mediated Overexpression of Neuroserpin in the Hippocampus Decreases PSD-95 Expression but Does Not Affect Hippocampal-Dependent Learning and Memory
PLoS ONE·2014· 17 citedOpen Access
Stroke Patients Develop Antibodies That React With Components of <i>N</i> -Methyl- <scp>d</scp> -Aspartate Receptor Subunit 1 in Proportion to Lesion Size
Stroke·2013· 28 citedOpen Access
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Frequent Co-authors

Matthew J. During(20), P. Lawlor(13), Mike Dragunow(9), Dahna M. Fong(5), Paola Leone(5), Bronwen Connor(5), Matthias Klugmann(5), Michiko Kobayashi(4), Helen L. Fitzsimons(4), Jonathan R. Lamb(4), C. Wymond Symes(4), Ernest Sirimanne(4), Alexandre Mouravlev(4), M. Walton(4), Ross Bland(3), S F Wolf(3), Michael Dragunow(3), Richard L. M. Faull(3), Angela Mehlert(3), Jane Dunning(3)