Helen L. Fitzsimons

Massey University — New Zealand

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index3.9kcitations43works2.02yr avg
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Research Topics

RNA Interference and Gene Delivery(10), Virus-based gene therapy research(9), Histone Deacetylase Inhibitors Research(8), Neurobiology and Insect Physiology Research(7), Nerve injury and regeneration(5)

Publications43 total

N-terminal oligomerization drives HDAC4 nuclear condensation and neurodevelopmental dysfunction in <i>Drosophila</i>
Open Biology·2025Open Access
Author response for "N-terminal oligomerization drives HDAC4 nuclear condensation and neurodevelopmental dysfunction in &lt;i&gt;Drosophila&lt;/i&gt;"
2025
N-terminal oligomerization drives HDAC4 nuclear condensation and neurodevelopmental dysfunction in <i>Drosophila</i>
2025· 1 citedOpen Access
A novel three-dimensional model of infantile haemangioma
British Journal of Dermatology·2024· 1 cited
Recent advances in understanding the molecular basis of infantile haemangioma development
British Journal of Dermatology·2024· 8 citedOpen Access
Deciphering the roles of subcellular distribution and interactions involving the MEF2 binding region, the ankyrin repeat binding motif and the catalytic site of HDAC4 in Drosophila neuronal morphogenesis
BMC Biology·2024· 2 citedOpen Access
Comparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila
PubMed·2023· 10 citedOpen Access
Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila
Molecular Brain·2023· 20 citedOpen Access
Herzog is not required for mushroom body development or courtship learning &amp; memory but is required for eye development in Drosophila melanogaster
PubMed·2022· 2 citedOpen Access
Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration
Molecular Brain·2022· 4 citedOpen Access
Ankyrin2 is required for neuronal morphogenesis and long-term memory and interacts genetically with HDAC4
2021Open Access
EP400NL is required for cMyc-mediated PD-L1 gene activation by forming a transcriptional coactivator complex
2021Open Access
Increased Abundance of Nuclear HDAC4 Impairs Neuronal Development and Long-Term Memory
Frontiers in Molecular Neuroscience·2021· 30 citedOpen Access
Increased abundance of nuclear HDAC4 impairs neuronal development and long-term memory
2021· 4 citedOpen Access
The ERM protein Moesin is essential for neuronal morphogenesis and long-term memory in Drosophila
Molecular Brain·2017· 44 citedOpen Access
SymB and SymC, two membrane associated proteins, are required for <scp><i>E</i></scp><i>pichloë festucae</i> hyphal cell–cell fusion and maintenance of a mutualistic interaction with <scp><i>L</i></scp><i>olium perenne</i>
Molecular Microbiology·2016· 28 cited
An <i>Epichloë festucae</i> homologue of MOB3, a component of the STRIPAK complex, is required for the establishment of a mutualistic symbiotic interaction with <i>Lolium perenne</i>
Molecular Plant Pathology·2016· 24 citedOpen Access
Long-Term Memory in<i>Drosophila</i>Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9
Genetics·2016· 46 citedOpen Access
Towards next generation maggot debridement therapy: transgenic Lucilia sericata larvae that produce and secrete a human growth factor
BMC Biotechnology·2016· 77 citedOpen Access
The Class IIa histone deacetylase HDAC4 and neuronal function: Nuclear nuisance and cytoplasmic stalwart?
Neurobiology of Learning and Memory·2015· 40 cited
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Frequent Co-authors

Matthew J. During(14), Ross Bland(7), Maxwell J. Scott(6), Hannah R. Hawley(6), Deborah Young(5), Tracy K. Hale(5), Michael G. Kaplitt(4), P. Lawlor(4), Silvia Schwartz(4), Wei Jun Tan(4), Matthias Klugmann(3), M J During(3), Francesco M. Noè(3), Annamaria Vezzani(3), Sarah J. Wilson(3), Andrew J. Sutherland‐Smith(3), Matthew S. Savoian(3), Chengke Tang(2), David Eidelberg(2), David S. Zuzga(2)