Sannula Kesavardhana

Indian Institute of Science Bangalore — India

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index5.5kcitations45works4.42yr avg
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Research Topics

Inflammasome and immune disorders(20), interferon and immune responses(13), HIV Research and Treatment(7), Influenza Virus Research Studies(7), Cell death mechanisms and regulation(5)

Publications45 total

DDX3X syndrome mutations lock DDX3X-RNA conformational states to drive persistent pathological condensation and neuronal death
2026Open Access
Protocol for the detection of RHIM-protein oligomeric complex formation using DSP-mediated crosslinking in HEK293T cultured cells
STAR Protocols·2025Open Access
Programmed cell revival from imminent cell death enhances tissue repair and regeneration
The EMBO Journal·2025· 4 citedOpen Access
Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential
Microbiology Spectrum·2025· 3 citedOpen Access
Disassembly of ALS condensates by a disordered peptide
2025· 1 citedOpen Access
Bat adaptations in inflammation and cell death regulation contribute to viral tolerance
mBio·2025· 10 citedOpen Access
Z‐<scp>Nucleic Acid</scp> Sensing and Activation of <scp>ZBP1</scp> in Cellular Physiology and Disease Pathogenesis
Immunological Reviews·2025· 15 citedOpen Access
Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling
iScience·2024· 7 citedOpen Access
PANoptosis Regulation in Reservoir Hosts of Zoonotic Viruses
Viruses·2024· 1 citedOpen Access
Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential
2024Open Access
Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential
2024· 1 citedOpen Access
H5N1 influenza: Urgent questions and directions
Cell·2024· 11 citedOpen Access
Avian influenza virus neuraminidase stalk length and haemagglutinin glycosylation patterns reveal molecularly directed reassortment promoting the emergence of highly pathogenic clade 2.3.4.4b A (H5N1) viruses
2024· 9 citedOpen Access
Virologic Determinants Promoting the Molecularly Directed Reassortment and the Emergence of Highly Pathogenic Clade 2.3.4.4b A (H5N1) Viruses
SSRN Electronic Journal·2024Open Access
Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling
2023· 2 citedOpen Access
Emerging Role of ZBP1 in Z-RNA Sensing, Influenza Virus-Induced Cell Death, and Pulmonary Inflammation
mBio·2022· 57 citedOpen Access
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection
The Journal of Immunology·2021· 34 citedOpen Access
Inflammasome regulation in driving COVID-19 severity in humans and immune tolerance in bats
Journal of Leukocyte Biology·2021· 19 citedOpen Access
DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response
Journal of Biological Chemistry·2021· 55 citedOpen Access
Dysregulated Innate Immune and Inflammatory Responses in SARS-CoV-2 Infection and COVID-19 Severity
Critical Reviews in Immunology·2021· 2 citedOpen Access
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Frequent Co-authors

Thirumala‐Devi Kanneganti(19), R. K. Subbarao Malireddi(13), Rajendra Karki(9), Amanda R. Burton(8), Raghavan Varadarajan(8), Ayushi Amin Dey(7), Peter Vogel(6), Sanchita Mishra(6), David E. Place(5), Bhesh Raj Sharma(5), Parimal Samir(5), Ranjana Nataraj(5), Benoit Briard(4), Sahana Nagaraja(4), Disha Jain(4), Teneema Kuriakose(3), Si Ming Man(3), S. William Pelletier(3), Shondra M. Pruett‐Miller(3), Raksha Das(3)