Bhesh Raj Sharma

St. Jude Children's Research Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index6.8kcitations62works27.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Inflammasome and immune disorders(33), interferon and immune responses(15), IL-33, ST2, and ILC Pathways(7), Immune Response and Inflammation(6), Natural Antidiabetic Agents Studies(6)

Publications62 total

Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Cell·2025· 10 citedOpen Access
Innate immune sensor NLRP3 drives PANoptosome formation and PANoptosis
The Journal of Immunology·2025· 24 citedOpen Access
Extracellular vesicles transport gasdermin pores, amplifying inflammatory cell death
Trends in Immunology·2025· 1 citedOpen Access
Innate Immunity in Protection and Pathogenesis During Coronavirus Infections and COVID-19
Annual Review of Immunology·2024· 29 citedOpen Access
NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress
Nature Communications·2024· 71 citedOpen Access
ZBP1 Drives IAV-Induced NLRP3 Inflammasome Activation and Lytic Cell Death, PANoptosis, Independent of the Necroptosis Executioner MLKL
Viruses·2023· 43 citedOpen Access
Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis)
Journal of Biological Chemistry·2023· 83 citedOpen Access
Nelumbo nucifera Leaf Extract Regulates Lipid Metabolism and Differentiation in 3T3-L1 Adipocytes and db/db Mice
Natural Product Sciences·2022· 3 citedOpen Access
Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression
Frontiers in Immunology·2022· 7 citedOpen Access
Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
Cell Reports·2022· 33 citedOpen Access
Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology
NAR Cancer·2022· 46 citedOpen Access
Inflammasome signaling in colorectal cancer
Translational research·2022· 74 citedOpen Access
Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression
2022Open Access
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection
Science Immunology·2022· 290 citedOpen Access
The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis
Cancers·2022· 21 citedOpen Access
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
Cell Reports·2021· 365 citedOpen Access
NLRP3 inflammasome in cancer and metabolic diseases
Nature Immunology·2021· 1.0k citedOpen Access
DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response
Journal of Biological Chemistry·2021· 55 citedOpen Access
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
Cell·2020· 1.6k citedOpen Access
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.
PubMed·2020· 40 citedOpen Access
page 1 of 4Next →

Frequent Co-authors

Thirumala‐Devi Kanneganti(31), Rajendra Karki(24), R. K. Subbarao Malireddi(17), Dong Young Rhyu(16), Peter Vogel(11), Parimal Samir(9), Balaji Banoth(8), Amanda R. Burton(7), Yaqiu Wang(7), Shraddha Tuladhar(6), Min Zheng(5), Balamurugan Sundaram(5), Geoffrey Neale(5), Sannula Kesavardhana(5), Richard J. Webby(4), Colleen B. Jonsson(4), David E. Place(4), Benoit Briard(4), Raghvendra Mall(4), Ein Lee(4)