Ruben J. G. Hulswit

Utrecht University — Netherlands

Medicine · Health Sciences

15h-index4.4kcitations21works1.02yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(12), Animal Virus Infections Studies(11), Viral gastroenteritis research and epidemiology(8), Viral Infections and Vectors(5), Virus-based gene therapy research(4)

Publications21 total

Cetacean coronavirus spikes highlight S glycoprotein structural plasticity
2025· 1 citedOpen Access
Sialoglycan binding triggers spike opening in a human coronavirus
Nature·2023· 74 citedOpen Access
Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses
Nature Communications·2023· 15 citedOpen Access
Identification of Evolutionary Trajectories Shared across Human Betacoronaviruses
Genome Biology and Evolution·2023· 6 citedOpen Access
Sialoglycan binding triggers spike opening in a human coronavirus
2023· 4 citedOpen Access
Identification of evolutionary trajectories shared across human betacoronaviruses
2021· 8 citedOpen Access
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil
Science·2021· 1.5k citedOpen Access
Antibody evasion by the P.1 strain of SARS-CoV-2
Cell·2021· 655 citedOpen Access
Recent Advances in Bunyavirus Glycoprotein Research: Precursor Processing, Receptor Binding and Structure
Viruses·2021· 79 citedOpen Access
Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein
eLife·2020· 26 citedOpen Access
Naturally Acquired Rift Valley Fever Virus Neutralizing Antibodies Predominantly Target the Gn Glycoprotein
iScience·2020· 44 citedOpen Access
Identification of Common Deletions in the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2
Journal of Virology·2020· 178 citedOpen Access
Crystal structure of Puumala virus Gc in complex with Fab 4G2
2020
Human coronaviruses OC43 and HKU1 bind to 9- <i>O</i> -acetylated sialic acids via a conserved receptor-binding site in spike protein domain A
Proceedings of the National Academy of Sciences·2019· 410 citedOpen Access
Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility
Proceedings of the National Academy of Sciences·2018· 292 citedOpen Access
Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein
Proceedings of the National Academy of Sciences·2017· 358 citedOpen Access
Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity
Cell Host & Microbe·2017· 125 citedOpen Access
Coronavirus receptor switch explained from the stereochemistry of protein–carbohydrate interactions and a single mutation
Proceedings of the National Academy of Sciences·2016· 42 citedOpen Access
Coronavirus Spike Protein and Tropism Changes
Advances in virus research·2016· 482 citedOpen Access
Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins
Cell Reports·2015· 78 citedOpen Access
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Frequent Co-authors

Thomas A. Bowden(10), Frank J. M. van Kuppeveld(9), Berend‐Jan Bosch(7), Raoul J. de Groot(7), Yifei Lang(5), Oliver G. Pybus(4), Mark J. G. Bakkers(4), Zeshi Li(4), Geert‐Jan Boons(4), Eric G. Huizinga(4), Guido C. Paesen(4), Sergei L. Kosakovsky Pond(3), Wentao Li(3), Martijn A. Langereis(3), Joost Snijder(3), Daniel L. Hurdiss(3), Robert Stass(3), Nicholas J. Loman(2), Andrew Rambaut(2), Cornelis A. M. de Haan(2)