Frank J. M. van Kuppeveld

University of Applied Sciences Utrecht — Netherlands

Medicine · Health Sciences

78h-index19.6kcitations355works5.02yr avg
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Research Topics

Viral Infections and Immunology Research(160), Viral gastroenteritis research and epidemiology(77), RNA and protein synthesis mechanisms(69), SARS-CoV-2 and COVID-19 Research(65), Animal Virus Infections Studies(59)

Publications355 total

Cardiovirus-Mediated PKR inhibition results from nucleocytoplasmic trafficking disruption
PLoS Pathogens·2025Open Access
Visualizing infection by single positive-sense RNA viruses using virus infection real-time imaging (VIRIM)
Nature Protocols·2025
The gH/gL/gO Complex of Elephant Endotheliotropic Herpesvirus 1A Functions as a Receptor-Binding Complex
2025Open Access
Natural SARS-CoV-2 infections in farmed minks results in severe lung pathology and high viral loads in multiple organs
Journal of Comparative Pathology·2025Open Access
Allosteric Disordering of eIF2B Regulates the Integrated Stress Response
2025· 1 citedOpen Access
The multifaceted role of the viral 2A protease in enterovirus replication and antagonism of host antiviral responses
PLoS Pathogens·2025· 2 citedOpen Access
ITAF <sub>45</sub> is a pervasive <i>trans</i> -acting factor for picornavirus Type II IRES elements
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Cardiovirus-Mediated PKR Inhibition Results from Nucleocytoplasmic Trafficking Disruption
2025Open Access
Identification of β4GALNT2 as an anti-hPIV3 factor through genome-wide CRISPR/Cas9 library screening
Emerging Microbes & Infections·2025· 2 citedOpen Access
Hunting-training dogs and companion dogs in the Netherlands are frequently exposed to highly pathogenic avian influenza (HPAI H5) and human H1N1 virus, 2021–2023
One Health·2025· 2 citedOpen Access
Identification of picornavirus proteins that inhibit de novo nucleotide synthesis during infection
PLoS Pathogens·2025Open Access
Safety and efficacy of live attenuated PEDV vaccines for neonatal protection
npj Vaccines·2025· 1 citedOpen Access
Integrative Structure of Norovirus NS3 Suggests a Role in RNA Transport
2025· 1 citedOpen Access
Molecular basis of autoimmune disease protection by MDA5 variants
Cell Reports·2025· 3 citedOpen Access
Peptidomimetic Phenoxymethyl Ketone Warheads as Potent Dual-Mode Inhibitors against SARS-CoV-2 M<sup>pro</sup> and Cathepsin
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Cetacean coronavirus spikes highlight S glycoprotein structural plasticity
2025· 1 citedOpen Access
Cell-based sialoglycan arrays for directly comparing influenza A virus receptor requirements for binding and infection
iScience·2025Open Access
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein
UNC Libraries·2025Open Access
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein
Nature·2025· 19 citedOpen Access
A coronavirus assembly inhibitor that targets the viral membrane protein
Nature·2025· 18 citedOpen Access
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Frequent Co-authors

Berend‐Jan Bosch(12), Kjerstin Lanke(10), Wentao Li(9), Bart L. Haagmans(8), Willem J. G. Melchers(8), Jeroen R. P. M. Strating(6), Raoul J. de Groot(6), Peter J. M. Rottier(6), Cornelis A. M. de Haan(6), Martijn A. Langereis(6), Hilde M. van der Schaar(6), Hendrik Jan Thibaut(5), Feng Qian(5), Chunyan Wang(4), Dubravka Drabek(4), Nisreen M.A. Okba(4), Rien van Haperen(4), Frank Grosveld(4), Ruben J. G. Hulswit(4), Ivy Widjaja(4)