Damián Kovalovsky

United Therapeutics (United States) — United States

Immunology and Microbiology · Life Sciences

20h-index2.0kcitations42works10.52yr avg
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Research Topics

Immune Cell Function and Interaction(17), T-cell and B-cell Immunology(15), CAR-T cell therapy research(8), Nuclear Receptors and Signaling(6), Immune Response and Inflammation(5)

Publications42 total

The HDAC6 inhibitor AVS100 (SS208) induces a pro-inflammatory tumor microenvironment and potentiates immunotherapy
Science Advances·2024· 21 citedOpen Access
Abstract 1421: The HDAC6-specific inhibitor AVS100 (SS208) blocks M2 polarization of tumor associated macrophages and potentiates immunotherapy in preclinical tumor models
Cancer Research·2024
Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis
Science Immunology·2022· 16 citedOpen Access
Expression of a BTB-ZF transcription factor controls the function of an innate-like Tregs essential for intestinal homeostasis
The Journal of Immunology·2022
Increased Activity of a NK-Specific CAR-NK Framework Targeting CD3 and CD5 for T-Cell Leukemias
Cancers·2022· 22 citedOpen Access
From Hematopoietic Stem Cell Transplantation to Chimeric Antigen Receptor Therapy: Advances, Limitations and Future Perspectives
Cells·2021· 12 citedOpen Access
Specific expression of a BTB-ZF transcription factor defines innate-like regulatory T cells that are essential for intestinal homeostasis
The Journal of Immunology·2021
Siglec-6 is a target for chimeric antigen receptor T-cell treatment of chronic lymphocytic leukemia
Leukemia·2021· 22 citedOpen Access
Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis
Journal for ImmunoTherapy of Cancer·2019· 54 citedOpen Access
PLZF play as an indirect facilitator of thymic retention for the innate-like T-cells to aquire innate-like functions
Cell Death and Disease·2018· 3 citedOpen Access
Reciprocal suppression between Zbtb1 expression and IL‐7Rα signalling during T‐cell development
Journal of Cellular and Molecular Medicine·2018· 4 citedOpen Access
Zbtb1 controls NKp46+ ROR-gamma-T+ innate lymphoid cell (ILC3) development
Oncotarget·2017· 7 citedOpen Access
Abstract 4622: Characterization of sulfatide reactive type II NKT cells from mouse lung
Cancer Research·2017
Zbtb1 prevents default myeloid differentiation of lymphoid-primed multipotent progenitors
Oncotarget·2016· 10 citedOpen Access
Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors
The Journal of Immunology·2016· 17 citedOpen Access
Production of the Semi-Invariant TCR and PLZF Function in Innate Programming of iNKT Cells
Elsevier eBooks·2016
PLZF Controls the Development of Fetal-Derived IL-17+Vγ6+ γδ T Cells
The Journal of Immunology·2015· 79 citedOpen Access
Ectopic T Cell Receptor-α Locus Control Region Activity in B Cells Is Suppressed by Direct Linkage to Two Flanking Genes at Once
PLoS ONE·2010· 4 citedOpen Access
PLZF Induces the Spontaneous Acquisition of Memory/Effector Functions in T Cells Independently of NKT Cell-Related Signals
The Journal of Immunology·2010· 87 citedOpen Access
A Novel TCR Transgenic Model Reveals That Negative Selection Involves an Immediate, Bim-Dependent Pathway and a Delayed, Bim-Independent Pathway
PLoS ONE·2010· 33 citedOpen Access
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Frequent Co-authors

Derek B. Sant’Angelo(14), Eduardo Arzt(11), Marcelo Páez-Pereda(9), Günter K. Stalla(8), Herta Flor(6), Ying Lu(6), Xin Cao(5), Xianyu Zhang(5), Damián Refojo(3), Marco Losa(3), Zhuyan Guo(3), Marei Dose(3), Fotini Gounari(3), Eirini P. Papapetrou(3), Laurent Belœil(3), Michel Sadelain(3), Carolina Perez Castro(3), Benjamin Ortiz(3), Elisaveta Voynova(3), Agata Krzyzanowska(3)