Ana Gallego-Lleyda

Universidad de Zaragoza — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index540citations16works4.32yr avg
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Research Topics

RNA Interference and Gene Delivery(10), Cell death mechanisms and regulation(8), Extracellular vesicles in disease(5), Advanced biosensing and bioanalysis techniques(3), Immune Cell Function and Interaction(3)

Publications16 total

Multicomponent thiolactone-based ionizable lipid screening platform for efficient and tunable mRNA delivery to the lungs
Communications Chemistry·2025· 6 citedOpen Access
Predictive Lung- and Spleen-Targeted mRNA Delivery with Biodegradable Ionizable Lipids in Four-Component LNPs
Pharmaceutics·2025· 8 citedOpen Access
STAAR Lipids: A Novel Ionizable Lipid Synthetic Platform for Efficient mRNA Delivery In Vivo with Tunable Lung Targeting
2024Open Access
Multicomponent Thiolactone-Based Ionizable Lipid Screening Platform for an Efficient and Tunable mRNA Delivery to the Lungs
2024· 3 citedOpen Access
Double-Edged Lipid Nanoparticles Combining Liposome-Bound TRAIL and Encapsulated Doxorubicin Showing an Extraordinary Synergistic Pro-Apoptotic Potential
Cancers·2019· 19 citedOpen Access
Importance of TRAIL Molecular Anatomy in Receptor Oligomerization and Signaling. Implications for Cancer Therapy
Cancers·2019· 55 citedOpen Access
Role of Exosomes in the Regulation of T-Cell Mediated Immune Responses and in Autoimmune Disease
Cells·2019· 161 citedOpen Access
Role of Exosomes in the Regulation of T-cell Mediated Immune Responses and in Autoimmune Disease
Preprints.org·2018· 3 citedOpen Access
Lipid Nanoparticles Decorated with TNF-Related Aptosis-Inducing Ligand (TRAIL) Are More Cytotoxic than Soluble Recombinant TRAIL in Sarcoma
International Journal of Molecular Sciences·2018· 22 citedOpen Access
High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 cross-linking and increases antitumour effect against colon cancer
Cancer Letters·2016· 55 cited
Improved Anti-Tumor Activity of Novel Highly Bioactive Liposome-Bound TRAIL in Breast Cancer Cells
Recent Patents on Anti-Cancer Drug Discovery·2016· 12 cited
Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein
Oncotarget·2016· 52 citedOpen Access
TRAIL-coated lipid-nanoparticles overcome resistance to soluble recombinant TRAIL in non-small cell lung cancer cells
Nanotechnology·2016· 39 cited
Death Ligands and Granulysin: Mechanisms of Tumor Cell Death Induction and Therapeutic Opportunities
Immunotherapy·2015· 24 cited
Immunotherapy with liposome-bound TRAIL overcomes partial protection to soluble TRAIL-induced apoptosis offered by down-regulation of Bim in leukemic cells
Clinical & Translational Oncology·2015· 31 cited
Liposome-bound TRAIL induces superior DR5 clustering and enhanced DISC recruitment in histiocytic lymphoma U937 cells
Leukemia Research·2015· 50 cited

Frequent Co-authors

Diego de Miguel(15), Alberto Anel(12), Luis Martínez‐Lostao(12), Javier Naval(4), Juan Heredero(4), Beatriz Blandín(4), Teresa Alejo(4), Diego Casabona(4), Esther Pérez‐Herrán(4), Juan Martínez-Oliván(4), Javier Giménez-Warren(4), José M. Ayuso(3), Luis J. Fernández(3), Ignacio Ochoa(3), Elena Mata(3), Alfonso Toro(3), Alexandre López(3), Isabel Marzo(2), Blanca Conde(2), Álvaro Peña(2)