Javier Naval

Universidad de Zaragoza — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

42h-index6.0kcitations125works0.82yr avg
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Research Topics

Cell death mechanisms and regulation(40), Multiple Myeloma Research and Treatments(17), RNA Interference and Gene Delivery(17), Immune Cell Function and Interaction(16), Fatty Acid Research and Health(10)

Publications125 total

NK92 cells stably transfected with CD16 are efficient against multiple myeloma cells <i>ex vivo</i> and <i>in vivo</i> , especially if combined with daratumumab
OncoImmunology·2025· 1 citedOpen Access
Alisertib and Barasertib Induce Cell Cycle Arrest and Mitochondria-Related Cell Death in Multiple Myeloma with Enhanced Efficacy Through Sequential Combination with BH3-Mimetics and Panobinostat
Cancers·2025Open Access
Efficient in vivo anti-tumoral effect of the anti-CEA, granulysin-based immunotoxin MFE23GRNLY in a lung adenocarcinoma model. Combination with a Bcl-xL-selective BH3 mimetic
2025Open Access
Cytofluorometric assessment of calreticulin exposure on CD38+ plasma cells from the human bone marrow
Methods in cell biology·2024· 2 citedOpen Access
Dinaciclib synergizes with <scp>BH3</scp> mimetics targeting <scp>BCL</scp>‐2 and <scp>BCL‐X<sub>L</sub></scp> in multiple myeloma cell lines partially dependent on <scp>MCL</scp>‐1 and in plasma cells from patients
Molecular Oncology·2023· 4 citedOpen Access
Study of the Bcl-2 Interactome by BiFC Reveals Differences in the Activation Mechanism of Bax and Bak
Cells·2023· 7 citedOpen Access
Ecto-calreticulin expression in multiple myeloma correlates with a failed anti-tumoral immune response and bad prognosis
OncoImmunology·2022· 10 citedOpen Access
Harnessing the Potential of NK Cell-Based Immunotherapies against Multiple Myeloma
Cells·2022· 17 citedOpen Access
Future prospects for mitosis-targeted antitumor therapies
Biochemical Pharmacology·2021· 50 citedOpen Access
Expanded NK cells from umbilical cord blood and adult peripheral blood combined with daratumumab are effective against tumor cells from multiple myeloma patients
OncoImmunology·2020· 39 citedOpen Access
Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance
Scientific Reports·2020· 37 citedOpen Access
Novel Forms of Immunomodulation for Cancer Therapy
Trends in cancer·2020· 23 cited
Response: Commentary: Immunogenic Cell Death and Immunotherapy of Multiple Myeloma
Frontiers in Cell and Developmental Biology·2019· 6 citedOpen Access
A giant retroperitoneal liposarcoma with renal involvement: A case report and literature review
Gastroenterología y Hepatología (English Edition)·2019· 1 cited
Immunogenic Cell Death and Immunotherapy of Multiple Myeloma
Frontiers in Cell and Developmental Biology·2019· 192 citedOpen Access
Importance of TRAIL Molecular Anatomy in Receptor Oligomerization and Signaling. Implications for Cancer Therapy
Cancers·2019· 55 citedOpen Access
Liposarcoma retroperitoneal gigante con afectación renal: reporte de un caso y revisión de la literatura
Gastroenterología y Hepatología·2019· 8 cited
Role of Exosomes in the Regulation of T-Cell Mediated Immune Responses and in Autoimmune Disease
Cells·2019· 161 citedOpen Access
Role of Exosomes in the Regulation of T-cell Mediated Immune Responses and in Autoimmune Disease
Preprints.org·2018· 3 citedOpen Access
APO2L/TRAIL
2017
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Frequent Co-authors

Alberto Anel(34), Isabel Marzo(22), Andrés Piñeiro(17), Susana Gamen(11), María José Martínez‐Lorenzo(8), María A. Álava(8), Julián Pardo(8), Pilar Lasierra(7), Luis Larrad(7), Luis Martínez‐Lostao(7), J Uriel(5), Alberto Bosque(4), Diego de Miguel(4), Martín Villalba(4), Inmaculada Monleón(3), Marı́a Iturralde(3), Ana Gallego-Lleyda(3), M.A. Álava(3), José Uriel(3), Patricia Balsas(3)