Ortal Iancu

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index334citations15works0.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

CRISPR and Genetic Engineering(8), Genetics and Neurodevelopmental Disorders(5), Virus-based gene therapy research(3), CAR-T cell therapy research(3), Cytomegalovirus and herpesvirus research(2)

Publications15 total

Abstract 4057: Beyond IL-2: The promise of anti PD-1-attenuated IL-2 fusion protein in cancer immunotherapy
Cancer Research·2024
CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications
Nature Communications·2023· 20 citedOpen Access
Data from WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma
2023Open Access
Supplementary Data from WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma
2023Open Access
Data from WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma
2023Open Access
Supplementary Data from WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma
2023Open Access
CRISPR-Cas9 RAG2 Correction via Coding Sequence Replacement to Preserve Endogenous Gene Regulation and Locus Structure
2023· 1 citedOpen Access
Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs
Molecular Therapy — Nucleic Acids·2022· 36 citedOpen Access
Multiplex HDR for Disease and Correction Modeling of SCID by CRISPR Genome Editing in Human HSPCs
2022Open Access
Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients
Nature Communications·2022· 97 citedOpen Access
High-Throughput Imaging of CRISPR- and Recombinant Adeno-Associated Virus–Induced DNA Damage Response in Human Hematopoietic Stem and Progenitor Cells
The CRISPR Journal·2022· 23 citedOpen Access
CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data
Nature Communications·2021· 38 citedOpen Access
Chemical Modification of Guide RNAs for Improved CRISPR Activity in CD34+ Human Hematopoietic Stem and Progenitor Cells
Methods in molecular biology·2020· 9 cited
Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System
Molecular Therapy — Methods & Clinical Development·2020· 66 citedOpen Access
WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma
Cancer Research·2016· 44 citedOpen Access

Frequent Co-authors

Ayal Hendel(9), Daniel Allen(7), Sara Del Mare(5), Hussam Husanie(5), Mohammad Abu-Odeh(5), Konstantinos Evangelou(5), Francesca Lovat(5), Stefano Volinia(5), Gail Amir(5), Janet L. Stein(5), Gary S. Stein(5), Carlo M. Croce(5), Vassilis G. Gorgoulis(5), Jane B. Lian(5), Rami I. Aqeilan(5), Katia Beider(5), Arnon Nagler(5), Orli Knop(4), Yu Nee Lee(4), Raz Somech(4)