Paula I. Seoane

Manchester Academic Health Science Centre — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index596citations19works4.32yr avg
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Research Topics

Inflammasome and immune disorders(6), Parasitic infections in humans and animals(6), Parasitic Infections and Diagnostics(5), Fungal Infections and Studies(4), Antifungal resistance and susceptibility(2)

Publications19 total

The secretion of interleukin-1β
Cytokine & Growth Factor Reviews·2025· 6 citedOpen Access
Lysosome positioning affects NLRP3 inflammasome activation
2025· 1 citedOpen Access
Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions
Nature Communications·2024· 6 citedOpen Access
Squaramides enhance NLRP3 inflammasome activation by lowering intracellular potassium
Cell Death Discovery·2023· 3 citedOpen Access
Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome
Science Signaling·2023· 47 citedOpen Access
NLRP3 activation in response to disrupted endocytic traffic
2021· 8 citedOpen Access
The NLRP3–inflammasome as a sensor of organelle dysfunction
The Journal of Cell Biology·2020· 180 citedOpen Access
Viral infection triggers interferon-induced expulsion of live Cryptococcus neoformans by macrophages
PLoS Pathogens·2020· 29 citedOpen Access
Vomocytosis: What we know so far
Cellular Microbiology·2019· 33 cited
Particles from the Echinococcus granulosus Laminated Layer Inhibit CD40 Upregulation in Dendritic Cells by Interfering with Akt Activation
Infection and Immunity·2019· 35 citedOpen Access
Inefficient and abortive classical complement pathway activation by the calcium inositol hexakisphosphate component of the Echinococcus granulosus laminated layer
Immunobiology·2019· 12 cited
Viral infection enhances vomocytosis of intracellular fungi via Type I interferons
2019· 3 citedOpen Access
Characterizing the Mechanisms of Nonopsonic Uptake of Cryptococci by Macrophages
The Journal of Immunology·2018· 36 citedOpen Access
The M2 triangle: gp130 binding cytokines drive macrophages to promote tumor growth
Immunology and Cell Biology·2018· 2 citedOpen Access
Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5
Science Advances·2017· 59 citedOpen Access
Particles from the Echinococcus granulosus laminated layer inhibit IL-4 and growth factor-driven Akt phosphorylation and proliferative responses in macrophages
Scientific Reports·2016· 30 citedOpen Access
The laminated layer: Recent advances and insights into Echinococcus biology and evolution
Experimental Parasitology·2015· 51 citedOpen Access
Modulación de los efectos de la interleuquina 4 en macrófagos y células dendríticas por un particulado de la capa laminar de Echinococcus granulosus
Americanae (AECID Library)·2015
Unconventional Maturation of Dendritic Cells Induced by Particles from the Laminated Layer of Larval Echinococcus granulosus
Infection and Immunity·2014· 55 citedOpen Access

Frequent Co-authors

David Brough(7), Christopher Hoyle(5), Gloria López‐Castejón(5), Martin Lowe(5), Robin C. May(5), Álvaro Díaz(5), Cecilia Casaravilla(4), Álvaro Pittini(4), Dominik Rückerl(4), Judith E. Allen(4), Jack Green(4), Hayley Bennett(4), Antony Adamson(4), Rose Wellens(3), L. Smith(3), Andrew S. MacDonald(2), Bali Lee(2), Fatima Martín‐Sánchez(2), Daniel M. Williams(2), Billie J. Matchett(2)