Mack B. Reynolds

Salk Institute for Biological Studies — United States

Immunology and Microbiology · Life Sciences

10h-index234citations24works7.82yr avg
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Research Topics

Immune Response and Inflammation(7), Immune cells in cancer(7), Immune Cell Function and Interaction(6), Mitochondrial Function and Pathology(4), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(4)

Publications24 total

In vivo itaconate tracing reveals degradation pathway and turnover kinetics
Nature Metabolism·2025· 7 citedOpen Access
Multi-site phosphorylation of BCL2L13 in a TBK1- and AMPK-dependent manner reveals new modes of mitophagy regulation
2025· 2 citedOpen Access
IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity
Cell Reports·2025· 7 citedOpen Access
Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
Science Immunology·2025· 27 citedOpen Access
STARD7 maintains intestinal epithelial mitochondria architecture, barrier integrity, and protection from colitis
JCI Insight·2024· 10 citedOpen Access
Author Reply to Peer Reviews of Non-canonical activation of IRE1a during Candida albicans infection enhances macrophage fungicidal activity
2024
Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection
Cell Reports·2024· 17 citedOpen Access
011 Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
Journal of Investigative Dermatology·2024Open Access
489 Cutaneous IFN-κ expression drives nitric oxide-mediated macrophage metabolic remodeling during Staphylococcus aureus infection
Journal of Investigative Dermatology·2024
ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
Cell Reports·2024· 11 citedOpen Access
Iron regulates the quiescence of naive CD4 T cells by controlling mitochondria and cellular metabolism
Proceedings of the National Academy of Sciences·2024· 12 citedOpen Access
Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
2024· 6 citedOpen Access
Type I interferon governs immunometabolic checkpoints that coordinate inflammation during <i>Staphylococcal</i> infection
2024· 2 citedOpen Access
Non-canonical activation of IRE1α during <i>Candida albicans</i> infection enhances macrophage fungicidal activity
2023Open Access
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation
Science Advances·2023· 36 citedOpen Access
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II assembly and stability
2022· 1 citedOpen Access
Amino acids suppress macropinocytosis and promote release of CSF1 receptor in macrophages
Journal of Cell Science·2022· 9 citedOpen Access
The Mitochondrial Fission Regulator DRP1 Controls Post-Transcriptional Regulation of TNF-α
Frontiers in Cellular and Infection Microbiology·2021· 29 citedOpen Access
An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes
The Journal of Immunology·2020· 14 citedOpen Access
Cardiolipin dynamics regulate proinflammatory cytokine production in methicillin-resistant <i>Staphylococcus aureus-</i>-infected macrophages
The Journal of Immunology·2020· 2 cited
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Frequent Co-authors

Mary O’Riordan(13), Britton C Michmerhuizen(7), Costas A. Lyssiotis(7), Jonathan Z. Sexton(6), Benjamin Klein(6), Michael J. McFadden(6), Basel H. Abuaita(5), Tracey L. Schultz(5), Teresa R. O’Meara(5), Scott I. Simon(5), J. Michelle Kahlenberg(4), Lloyd Miller(4), Li Zhang(3), Mehrnaz Gharaee‐Kermani(3), Céline C. Berthier(3), Jessica L. Turnier(3), Jóhann E. Guðjónsson(3), Leif Anderson(3), Kathryn R. Rivara(3), Einar B. Ólafsson(3)