Ho-June Lee

Biochemistry, Genetics and Molecular Biology · Life Sciences

5h-index890citations15works0.62yr avg
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Research Topics

Hippo pathway signaling and YAP/TAZ(11), DNA Repair Mechanisms(3), Ubiquitin and proteasome pathways(2), Lipid metabolism and biosynthesis(2), Cell death mechanisms and regulation(1)

Publications15 total

Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2024· 2 citedOpen Access
Author response: Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2024Open Access
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2024· 1 citedOpen Access
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2024· 1 citedOpen Access
Reviewer #3 (Public Review): Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2024Open Access
Reviewer #2 (Public Review): Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2024Open Access
Reviewer #1 (Public Review): Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2024Open Access
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
2023Open Access
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
Nature Cancer·2023· 170 citedOpen Access
Data from Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells
2023Open Access
Data from Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells
2023Open Access
Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways
Cancer Discovery·2020· 55 citedOpen Access
The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors
Science Signaling·2018· 87 cited
Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells
Molecular Cancer Therapeutics·2017· 25 cited
Drug Resistance via Feedback Activation of Stat3 in Oncogene-Addicted Cancer Cells
Cancer Cell·2014· 549 citedOpen Access

Frequent Co-authors

Victoria C. Pham(12), Thijs J. Hagenbeek(11), Matthew T. Chang(11), Anwesha Dey(11), Jennifer A. Lacap(10), Scott E. Martin(10), Trang H. Pham(10), Zora Modrušan(10), Jason Li(10), Jennifer E. Klomp(9), Cameron L. Noland(9), Xiaosai Yao(9), Saundra Clausen(9), Wendy Lee(9), Paul Beroza(9), Rina Fong(9), Marta H. Kubala(9), Maria Lorenzo(9), Xin Ye(9), James J. Crawford(9)