Perle Totoson

Inserm — France

Medicine · Health Sciences

19h-index1.1kcitations81works1.22yr avg
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Research Topics

Rheumatoid Arthritis Research and Therapies(15), Systemic Lupus Erythematosus Research(13), Inflammatory mediators and NSAID effects(8), Spondyloarthritis Studies and Treatments(7), Nitric Oxide and Endothelin Effects(6)

Publications81 total

Anti-arthritic and endothelial protective effects of Derris scandens extract in adjuvant-induced arthritis in rats
PLoS ONE·2025Open Access
Baicalein, a major component of the root of Oroxylum indicum (Bignoniaceae) vasodilates isolated pulmonary arteries through endothelium-dependent and -independent mechanisms
Phytochemistry Letters·2025
Bioprospecting for plant extracts with protective effects on endothelial function
Phytochemistry Letters·2025
Baicalein, a major component of the root of Oroxylum indicum (L.) Kurz (Bignoniaceae), inhibits phosphodiesterase 5 and vasodilates isolated pulmonary arteries through endothelium-independent mechanisms
Fitoterapia·2025· 1 cited
Naproxen and prednisolone reduced intestinal alteration and permeability and bacterial translocation in rat adjuvant-induced arthritis
Inflammopharmacology·2025
Nymphaea pubescens Willd. extract and its flavonoid constituents vasodilate rat isolated pulmonary artery via NO-sGC-cGMP pathway
Phytomedicine Plus·2025· 1 citedOpen Access
Baicalein, a Major Component of the Root of Oroxylum Indicum (L.) Kurz (Bignoniaceae), Inhibits Phosphodiesterase 5 and Vasodilates Isolated Pulmonary Arteries Through Endothelium-Independent Mechanisms
SSRN Electronic Journal·2025Open Access
Anxio-depressive phenotype and impaired memory in mice with a conditional knockout of brain-derived neurotrophic factor in endothelial cells
American Journal of Physiology-Cell Physiology·2024· 2 citedOpen Access
10047: Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries
Journal of Molecular and Cellular Cardiology Plus·2024Open Access
IL-33 et sécukinumab, un lien dans les altérations intestinales liées aux rhumatismes inflammatoires
Revue du Rhumatisme·2024
AB0179 IL 33 AND SECUKINUMAB, A LINK IN RHEUMATIC-RELATED GUT ALTERATION
Annals of the Rheumatic Diseases·2024
Vasorelaxant and hypotensive effects of an ethanolic extract of Nymphaea pubescens and its main compound quercetin 3-methyl ether 3′-O-β-xylopyranoside
Frontiers in Pharmacology·2024· 3 citedOpen Access
A treadmill exercise reduced cardiac fibrosis, inflammation and vulnerability to ischemia-reperfusion in rat pristane-induced arthritis
Life Sciences·2024· 8 cited
A revisited version of the disputatio for pharmacological training: An educational study
Therapies·2023Open Access
Phosphodiesterase 5 and Arginase Inhibitory Activities of the Extracts from Some Members of Nelumbonaceae and Nymphaeaceae Families
Molecules·2023· 5 citedOpen Access
The new quinazoline derivative (N-methyl-N-[(thiophen-2-yl)methyl]quinazoline-2,4-diamine) vasodilates isolated mesenteric arteries through endothelium-independent mechanisms and has acute hypotensive effects in Wistar rats
European Journal of Pharmacology·2023· 7 cited
Increased gut permeability and intestinal inflammation precede arthritis onset in the adjuvant-induced model of arthritis
Arthritis Research & Therapy·2023· 19 citedOpen Access
Relevance of circulating markers of endothelial activation for cardiovascular risk assessment in rheumatoid arthritis: a narrative review
Life Sciences·2022· 6 citedOpen Access
Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects
Vascular Pharmacology·2022· 6 cited
AB0111 EFFECT OF TOFACITINIB AND GLUCOCORTICOIDS ON INTESTINAL PERMEABILITY, EPITHELIAL DAMAGE AND BACTERIAL TRANSLOCATION IN RAT ADJUVANT-INDUCED ARTHRITIS
Annals of the Rheumatic Diseases·2022Open Access
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Frequent Co-authors

Céline Demougeot(45), Daniel Wendling(23), Christine Marie(15), Clément Prati(14), Frank Verhoeven(12), Anne Prigent‐Tessier(10), Hélène Martin(9), Romain Bordy(8), C. Girard(8), Kornkanok Ingkaninan(8), Prapapan Temkitthawon(8), Martin Pédard(7), Aurore Quirié(7), Krongkarn Chootip(7), Katy Maguin‐Gaté(6), Johnny Moretto(6), Maude Tournier-Nappey(5), Philippe Garnier(4), Maude Tournier(4), Célian Peyronnel(4)