Hélène Martin

Centre National de la Recherche Scientifique — France

Medicine · Health Sciences

30h-index2.6kcitations152works1.82yr avg
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Research Topics

Cholinesterase and Neurodegenerative Diseases(23), Computational Drug Discovery Methods(14), Synthesis and biological activity(14), Cytomegalovirus and herpesvirus research(14), Peroxisome Proliferator-Activated Receptors(9)

Publications151 total

Placental Extracellular Vesicles Exhibit Reduced Neurogenic Potential Linked to Changes in Their miRNA Landscape Upon HCMV Infection
Journal of Extracellular Biology·2026Open Access
First Sustainable One-Pot Tandem Hantzsch Multicomponent Reaction/Click Reaction Approach for Novel Multitarget-Directed Ligands in Alzheimer’s Disease
ACS Chemical Neuroscience·2025Open Access
1634P Quantifying the invisible: Circulating tumour fraction and ctDNA dynamics predict clinical outcome in the OPTIMEL trial
Annals of Oncology·2025
Targeted oral delivery of microencapsulated TNF-α siRNA in an experimental model of colitis
Drug Delivery and Translational Research·2025· 3 cited
Modifications of intestinal barrier dysfunction under tofacitinib administration in rat adjuvant arthritis
Joint Bone Spine·2025
Naproxen and prednisolone reduced intestinal alteration and permeability and bacterial translocation in rat adjuvant-induced arthritis
Inflammopharmacology·2025
Nrf2 Activation and Antioxidant Properties of Chromone-Containing MTDLs for Alzheimer’s Disease Treatment
Molecules·2025· 4 citedOpen Access
Human placental models for studying viral infections
Current Opinion in Virology·2025· 1 citedOpen Access
10047: Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries
Journal of Molecular and Cellular Cardiology Plus·2024Open Access
Optimization and evaluation of gastroresistant microparticles designed for siRNA oral delivery
European Journal of Pharmaceutics and Biopharmaceutics·2024· 4 cited
Cinétique de l’inflammation et de la fibrose hépatique et effet d’un traitement précoce par anti-IL17A dans le modèle d’arthrite induite à l’adjuvant
Revue du Rhumatisme·2024
Synthesis and evaluation of lipoic acid – donepezil hybrids for Alzheimer’s disease using a straightforward strategy
Bioorganic & Medicinal Chemistry Letters·2024· 3 citedOpen Access
Discovery of New Highly Potent Histamine H<sub>3</sub> Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors
ACS Chemical Neuroscience·2024· 3 citedOpen Access
Efficient Two-Step Synthesis of Novel Pyrimido[4,5-d] Pyrimidines with Potent Neuroprotective, Antioxidant, and Aβ Anti-Aggregation Properties
Chemistry·2024Open Access
Circulating tumor DNA analysis in patients with BRAF-mutated metastatic cutaneous melanoma treated with BRAF and MEK inhibitors: Analysis of the OPTIMEL study.
Journal of Clinical Oncology·2024
Physical activity as an effective weapon against cardiac disorders in rheumatoid arthritis: A study in rat pristane-induced arthritis
Archives of cardiovascular diseases·2024
A treadmill exercise reduced cardiac fibrosis, inflammation and vulnerability to ischemia-reperfusion in rat pristane-induced arthritis
Life Sciences·2024· 8 cited
Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties
Pharmaceutics·2024· 6 citedOpen Access
1130P Tebentafusp (tebe) in an ongoing cohort of 72 French patients (pts) with metastatic uveal melanoma (mUM)
Annals of Oncology·2023· 1 citedOpen Access
The new quinazoline derivative (N-methyl-N-[(thiophen-2-yl)methyl]quinazoline-2,4-diamine) vasodilates isolated mesenteric arteries through endothelium-independent mechanisms and has acute hypotensive effects in Wistar rats
European Journal of Pharmacology·2023· 7 cited
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Frequent Co-authors

Christian Davrinche(11), Lhassane Ismaïli(11), José Marco‐Contelles(10), Alexandre Bonet(8), Lysiane Richert(7), Raphaël Cornu(6), Arnaud Béduneau(6), Alain Berthelot(5), Isabel Iriepa(5), Ignacio Moraleda(5), Fakher Chabchoub(5), Irène Pachón-Angona(4), Bernard Refouvelet(4), Vincent Luzet(4), Benjamin Rauwel(4), Céline Demougeot(4), Youssef Dgachi(4), Mourad Chioua(4), J.P. Sarsat(3), V. Albaladéjo(3)