Jochen Kuper

University of Würzburg — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index3.3kcitations98works4.12yr avg
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Research Topics

DNA Repair Mechanisms(29), DNA and Nucleic Acid Chemistry(15), Enzyme Structure and Function(14), RNA modifications and cancer(13), Metalloenzymes and iron-sulfur proteins(12)

Publications98 total

Search, verify and excise-lesion recognition in NER
DNA repair·2026Open Access
Anti-tumorigenic properties by trichothiodystrophy mutations in melanocytic cells
NAR Cancer·2025Open Access
Chemoproteomic analysis reveals RECQL4 as a mediator of nitroalkene-dependent double-strand break repair inhibition in cancer.
2025Open Access
Unlocking transcription-coupled DNA repair with the STK19 key
Molecular Cell·2024· 2 cited
Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene
Cancer Gene Therapy·2024· 7 citedOpen Access
XPD stalled on cross-linked DNA provides insight into damage verification
Nature Structural & Molecular Biology·2024· 11 citedOpen Access
G-quadruplex-mediated genomic instability drives SNVs in cancer
Nucleic Acids Research·2024· 13 citedOpen Access
Trapped in translocation – Stalling of XPD on a crosslinked DNA substrate
2024Open Access
G-quadruplex-mediated genomic instability drives SNVs in cancer
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
At the core of nucleotide excision repair
Current Opinion in Structural Biology·2023· 25 cited
Programmable DNA Interstrand Crosslinking by Alkene–Alkyne [2 + 2] Photocycloaddition
Journal of the American Chemical Society·2023· 12 cited
Computed structures of core eukaryotic protein complexes
Science·2021· 548 citedOpen Access
Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem
Scientific Reports·2021· 1 citedOpen Access
The novel <scp><i>KIT</i></scp> exon 11 germline mutation <scp>K558N</scp> is associated with gastrointestinal stromal tumor, mastocytosis, and seminoma development
Genes Chromosomes and Cancer·2021· 6 citedOpen Access
Three targets in one complex: A molecular perspective of TFIIH in cancer therapy
DNA repair·2021· 12 cited
The Interaction Efficiency of XPD-p44 With Bulky DNA Damages Depends on the Structure of the Damage
Frontiers in Cell and Developmental Biology·2021· 8 citedOpen Access
p62PH in potassium chloride
2021
HEWL in cesium chloride (1.71 M CsCl in cryo protectant)
2021
HEWL in cesium chloride (1.5 M CsCl in crystallization condition and cryo protectant)
2021
HEWL in cesium chloride (0.25 M CsCl in protein buffer and cryo protectant).
2021
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Frequent Co-authors

Caroline Kisker(32), Ralf R. Mendel(7), Günter Schwarz(6), Matthias Wilmanns(6), W. Koelmel(5), Bennett Van Houten(4), Hermann Schindelin(4), Florian Sauer(4), Stefanie C Wolski(3), Joshua A. Sommers(3), Robert M. Brosh(3), Cathy Braun(3), Dominik Schmitt(3), Arnaud Poterszman(3), Ángel Llamas(2), Hans‐Jürgen Hecht(2), Petra Hänzelmann(2), J.J. Truglio(2), Gudrun Michels(2), Agnes Elias(2)