W. David Wilson

Georgia State University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

74h-index20.4kcitations500works4.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(294), Advanced biosensing and bioanalysis techniques(146), RNA and protein synthesis mechanisms(93), RNA Interference and Gene Delivery(83), Synthesis and Biological Evaluation(75)

Publications499 total

OCA-B/Pou2af1 Expression in Mouse T Cells Promotes PD-1 Blockade-Induced Autoimmunity but is Dispensable for Anti-Tumor Immunity
2025
Alternative Approach to Sequence-Specific Recognition of DNA: Cooperative Stacking of Dication Dimers─Sensitivity to Compound Curvature, Aromatic Structure, and DNA Sequence
ACS Chemical Biology·2025· 3 citedOpen Access
Conserved Sequences from Dengue Virus Genomes Form Stable G-Quadruplexes
ACS Infectious Diseases·2024· 3 citedOpen Access
High-affinity A/T-rich DNA binding with a dimeric bisbenzamidine
NAR Molecular Medicine·2024Open Access
Structure of an RNA G-quadruplex from the West Nile virus genome
Nature Communications·2024· 17 citedOpen Access
Single GC base pair recognition by a heterocyclic diamidine: structures, affinities, and dynamics
RSC Advances·2024· 1 citedOpen Access
Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors
Structure·2023· 4 citedOpen Access
DNA selection by the master transcription factor PU.1
Cell Reports·2023· 14 citedOpen Access
X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences
ACS Bio & Med Chem Au·2023· 10 citedOpen Access
Binding to the DNA Minor Groove by Heterocyclic Dications: from AT Specific to GC Recognition Compounds
Current Protocols·2023· 9 cited
Investigation of the effect of structure modification of furamidine on the DNA minor groove binding and antiprotozoal activity
European Journal of Medicinal Chemistry·2023· 11 citedOpen Access
Compound Shape and Substituent Effects in DNA Minor Groove Interactions
2023· 2 cited
Reversible Small Molecule–Nucleic Acid Interactions
2022
Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines
Bioorganic & Medicinal Chemistry·2022· 9 citedOpen Access
Thermodynamic Factors That Drive Sequence-Specific DNA Binding of Designed, Synthetic Minor Groove Binding Agents
Life·2022· 7 citedOpen Access
Structural insights into the sequence preference of PU.1, a conserved helix-turn-helix transcription factor
Biophysical Journal·2022
Compound Shape and Substituent Effects in DNA Minor Groove Interactions
2022· 3 cited
DNA-facilitated target search by nucleoproteins: Extension of a biosensor-surface plasmon resonance method
Analytical Biochemistry·2021· 1 citedOpen Access
New antiparasitic flexible triaryl diamidines, their prodrugs and aza analogues: Synthesis, in vitro and in vivo biological evaluation, and molecular modelling studies
European Journal of Medicinal Chemistry·2021· 4 cited
Salt bridge dynamics in protein/DNA recognition: a comparative analysis of Elk1 and ETV6
Physical Chemistry Chemical Physics·2021· 4 citedOpen Access
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Frequent Co-authors

Farial A. Tanious(19), Stephen Neidle(9), David W. Boykin(8), David W. Boykin(8), James Edwin Hall(6), Mohamed A. Ismail(5), Richard R. Tidwell(5), Reto Brun(5), Lucjan Strękowski(4), Binh Nguyen(4), Anthony P. Reszka(3), Lynda Ratmeyer(3), Elizabeth W. White(3), Robert L. Jones(3), Chad E. Stephens(3), Mekala Gunaratnam(3), Brendan C. Bender(3), Donald R. McCurdy(3), Arvind Kumar(3), Ge� Xiao(2)