Binh Nguyen

Washington University in St. Louis — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index2.6kcitations85works4.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(38), DNA Repair Mechanisms(29), Bacterial Genetics and Biotechnology(14), Advanced biosensing and bioanalysis techniques(10), RNA Interference and Gene Delivery(10)

Publications85 total

ACLY inhibition promotes tumour immunity and suppresses liver cancer
Nature·2025· 15 citedOpen Access
Structural basis for dimerization and activation of UvrD-family helicases
Proceedings of the National Academy of Sciences·2025· 7 citedOpen Access
Phytochemical Analysis, Computational Study, and in vitro Assay of Etlingera elatior Inflorescence Extract Towards Inducible Nitric Oxide Synthase
Journal of Experimental Pharmacology·2025· 6 citedOpen Access
Expression of foetal gene Pontin is essential in protecting heart against pathological remodelling and cardiomyopathy
Nature Communications·2025· 2 citedOpen Access
BPS2025 - A functional cross-linked E. coli UvrD helicase dimer
Biophysical Journal·2025
BPS2025 - Single-stranded DNA translocation and DNA helicase activities of Mycobacterium tuberculosis UvrD1 dimers
Biophysical Journal·2025
Structural Basis for Dimerization and Activation of UvrD-family Helicases
2024Open Access
Subunit Communication within Dimeric SF1 DNA Helicases
Journal of Molecular Biology·2024· 5 citedOpen Access
Subunit Communication within Dimeric SF1 DNA Helicases
2024· 1 citedOpen Access
Mycobacterium tuberculosis Ku Stimulates Multi-round DNA Unwinding by UvrD1 Monomers
Journal of Molecular Biology·2023· 8 citedOpen Access
<i>Mycobacterium tuberculosis</i> Ku stimulates multi-round DNA unwinding by UvrD1 monomers
2023Open Access
“Helicase” activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein
Proceedings of the National Academy of Sciences·2023· 21 citedOpen Access
“Helicase” Activity Promoted Through Dynamic Interactions Between a ssDNA Translocase and a Diffusing SSB Protein
2022Open Access
How Glutamate Promotes Liquid-liquid Phase Separation and DNA Binding Cooperativity of E. coli SSB Protein
Journal of Molecular Biology·2022· 48 citedOpen Access
<i>Mycobacterium tuberculosis</i> DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine
Proceedings of the National Academy of Sciences·2022· 21 citedOpen Access
Regulation of Rep helicase unwinding by PriC and SSB
Biophysical Journal·2022
Mycobacterium tuberculosis DNA-repair helicase UvrD1 is activated by redox-dependent dimerization via a conserved 2b domain cysteine
Biophysical Journal·2022
How Glutamate Promotes Liquid-liquid Phase Separation and DNA Binding Cooperativity of <i>E. coli</i> SSB Protein
2022· 3 citedOpen Access
The <i>Mycobacterium tuberculosis</i> DNA-repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine conserved in other Actinobacteria
2021Open Access
Regulation of E. coli Rep helicase activity by PriC
Journal of Molecular Biology·2021· 24 citedOpen Access
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Frequent Co-authors

W. David Wilson(23), Timothy M. Lohman(15), Moses Lee(7), John A. Hartley(7), Alexander G. Kozlov(6), C. Caroline O’Hare(5), Hilary Mackay(5), Toni Brown(5), Fernando Rodrı́guez(4), Isabel Rozas(4), Elizabeth Weiland(4), Shawn E. Holt(4), Jérôme Kluza(4), Farial A. Tanious(3), Joshua E. Sokoloski(3), Stephen Neidle(3), Reto Brun(3), Christian Bailly(3), Karen L. Buchmueller(3), Cameron M. Howard(3)