Basant Abdulrahman

University of Calgary — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.2kcitations31works0.02yr avg
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Research Topics

Prion Diseases and Protein Misfolding(11), HIV Research and Treatment(7), Cystic Fibrosis Research Advances(7), Autophagy in Disease and Therapy(6), Vibrio bacteria research studies(5)

Publications31 total

Contrasting roles of autophagy in cellular prion infection
Autophagy·2025Open Access
Identification of Novel Insulin Resistance Related ceRNA Network in T2DM and Its Potential Editing by CRISPR/Cas9
International Journal of Molecular Sciences·2021· 15 citedOpen Access
dentification of novel insulin resistance related ceRNA network: LncRNA, RP11‐773H22.4; miR-3163, miR-1; mRNAs:RET , IGF1-R, m-TOR, GLUT-4, AKT2 in T2DM and its potential editing by CRISPR/Cas9
Research Square (Research Square)·2021Open Access
An astrocyte cell line that differentially propagates murine prions
Journal of Biological Chemistry·2020· 20 citedOpen Access
Sephin1 Reduces Prion Infection in Prion-Infected Cells and Animal Model
Molecular Neurobiology·2020· 16 cited
Metformin reduces prion infection in neuronal cells by enhancing autophagy
Biochemical and Biophysical Research Communications·2019· 20 cited
Autophagy pathways in the treatment of prion diseases
Current Opinion in Pharmacology·2019· 31 citedOpen Access
Combining autophagy stimulators and cellulose ethers for therapy against prion disease
Prion·2019· 31 citedOpen Access
Overexpression of quality control proteins reduces prion conversion in prion-infected cells
Journal of Biological Chemistry·2018· 15 citedOpen Access
Autophagy regulates exosomal release of prions in neuronal cells
Journal of Biological Chemistry·2018· 106 citedOpen Access
The autophagy inducers AR‐12 and AR‐14 control prion infection
The FASEB Journal·2018
The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions
Scientific Reports·2017· 31 citedOpen Access
Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro
Scientific Reports·2017· 19 citedOpen Access
Autophagy Controls Exosomal Release of Prions and Lateral Prion Infection
The FASEB Journal·2016· 1 cited
Heterozygosity for the F508del Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Attenuates Influenza Severity
The Journal of Infectious Diseases·2013· 22 citedOpen Access
Influenza‐induced cardiopulmonary dysfunction and alveolar fluid clearance inhibition are attenuated in F508del CFTRheterozygous mice
The FASEB Journal·2013
A bacterial protein promotes the recognition of the <i>L</i><i>egionella pneumophila</i> vacuole by autophagy
European Journal of Immunology·2013· 54 cited
Biofilm-derived Legionella pneumophila evades the innate immune response in macrophages
Frontiers in Cellular and Infection Microbiology·2013· 38 citedOpen Access
Depletion of the Ubiquitin-binding Adaptor Molecule SQSTM1/p62 from Macrophages Harboring cftr ΔF508 Mutation Improves the Delivery of Burkholderia cenocepacia to the Autophagic Machinery
Journal of Biological Chemistry·2012· 58 citedOpen Access
Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients
Biochemical and Biophysical Research Communications·2012· 52 citedOpen Access
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Frequent Co-authors

Dalia H. Abdelaziz(18), Amal O. Amer(14), Arwa Abu Khweek(12), Anwari Akhter(12), Hermann Schätzl(12), Kyle Caution(10), Simrika Thapa(8), Mark D. Wewers(7), Mikhail A. Gavrilin(6), Mia Tazi(6), Miguel A. Valvano(5), Sabine Gilch(5), Sheetal Kotrange(4), Benjamin T. Kopp(4), Hoda Hassan(4), Lu Li(4), Karen McCoy(3), Mahmoud Mostafa(3), Jaykumar Grandhi(3), Clay B. Marsh(3)