Panagiotis Ntziachristos

Ghent University Hospital — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index4.7kcitations168works1.52yr avg
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Research Topics

RNA Research and Splicing(33), RNA modifications and cancer(32), Acute Myeloid Leukemia Research(28), Acute Lymphoblastic Leukemia research(24), Epigenetics and DNA Methylation(23)

Publications168 total

Stable, thus in critical condition: m6A-methylated fusion transcripts in B-cell acute lymphoblastic leukemia
Haematologica·2026Open Access
<i>QKI</i> dysregulation induces extensive splicing changes in T-cell acute lymphoblastic leukemia
Haematologica·2026Open Access
TET2 mutations drive cell-autonomous type I interferon production and selective advantage through TRIM4 silencing
Blood·2025Open Access
Combinatorial targeting of metabolic vulnerabilities in t-cell leukemia through NAMPT inhibition
Blood·2025Open Access
NADPH controls a cell state vulnerability towards ferroptosis in acute lymphoblastic leukaemia
Blood·2025Open Access
T cell acute lymphoblastic leukemia exploits a neural proinflammatory pathway to colonize the meninges
Journal of Clinical Investigation·2025Open Access
NFATc1 and NFATc2 regulate glucocorticoid resistance in pediatric T-cell acute lymphoblastic leukemia through modulation of cholesterol biosynthesis and the WNT/β-catenin pathway
Haematologica·2025· 1 citedOpen Access
Underlying biology, challenges and emergent concepts in the treatment of relapsed and refractory pediatric T-cell acute lymphoblastic leukemia
Leukemia·2025Open Access
HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia
Blood·2025· 6 citedOpen Access
FTO regulates ELK3-mediated metabolic rewiring and represents a unique therapeutic target in T cell leukemia
Science Advances·2025· 3 citedOpen Access
Depletion of the RNA binding protein QKI and circular RNA dysregulation in T-cell acute lymphoblastic leukemia
Haematologica·2024· 1 citedOpen Access
Hnrnpc and m6a RNA Methylation Control Oncogenic Transcription and Metabolism in T-Cell Leukemia
Blood·2024Open Access
A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia
Science Advances·2024· 6 citedOpen Access
Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia
Blood·2024· 3 citedOpen Access
A succinylation switch to maligancy: SUCLG1, mitochondrial transcription and leukemia
The EMBO Journal·2024· 1 citedOpen Access
<i>Myb</i> overexpression synergizes with the loss of <i>Pten</i> and is a dependency factor and therapeutic target in T‐cell lymphoblastic leukemia
HemaSphere·2024· 3 citedOpen Access
Correction: A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia
Leukemia·2023· 1 citedOpen Access
Knocking off cancer’s HAT: CSS1477 disrupts oncogenic programs
Cell chemical biology·2023· 2 citedOpen Access
A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia
Leukemia·2023· 2 citedOpen Access
Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma
Haematologica·2023· 4 citedOpen Access
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Frequent Co-authors

Iannis Aifantis(24), Aristotelis Tsirigos(14), Pieter Van Vlierberghe(11), Thomas Trimarchi(9), Valentina Serafin(9), John D. Crispino(8), Charalampos Lazaris(7), Tim Pieters(7), Elisabeth Paietta(6), Cuijuan Han(6), Giuseppe Basso(6), Qi Jin(6), Alexandros Strikoudis(5), Blanca T. Gutierrez-Diaz(5), Bruno Palhais(5), Young Ah Goo(5), Igor Fijałkowski(5), Sofia Bakogianni(4), Yixing Zhu(4), Celestia Fang(4)