Tomohiro Numata

Jikei University School of Medicine — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index4.5kcitations126works1.82yr avg
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Research Topics

Ion channel regulation and function(35), Ion Channels and Receptors(32), Magnesium in Health and Disease(18), Neuroscience and Neuropharmacology Research(16), Photoreceptor and optogenetics research(11)

Publications126 total

Protective Effects of Panax ginseng Extract on Endothelin-1- and Isoproterenol-Induced Cardiac Hypertrophy via Maintenance of Mitochondrial Function and Calcium-Reactive Oxygen Species (ROS) Homeostasis
Cureus·2025Open Access
Atrial TRPM2 Channel-Mediated Ca2+ Influx Regulates ANP Secretion and Protects Against Isoproterenol-Induced Cardiac Hypertrophy and Fibrosis
Cells·2025· 1 citedOpen Access
Atrial TRPM2 Channel-Mediated Ca<sup>2+</sup> Influx Regulates ANP Secretion and Protects Against ISO-Induced Cardiac Hypertrophy and Fibrosis
Preprints.org·2025Open Access
Optogenetic and Endogenous Modulation of Ca2+ Signaling in Schwann Cells: Implications for Autocrine and Paracrine Neurotrophic Regulation
International Journal of Molecular Sciences·2025· 1 citedOpen Access
Optogenetic and Endogenous Modulation of Ca<sup>2+</sup> Signaling in Schwann Cells: Implications for Autocrine and Paracrine Neurotrophic Regulation
Preprints.org·2025· 3 citedOpen Access
Optogenetic Stimulation of Ca2+ Influx via Channelrhodopsin CapChR2 in Schwann Cells Promotes Neurite Outgrowth in Co-cultured PC12 Cells: A Neuronal Model
Cureus·2025· 1 citedOpen Access
Boi‐Ogi‐To, a Traditional Japanese Kampo Medicine, Promotes Cellular Excretion of Chloride and Water by Activating Volume‐Sensitive Outwardly Rectifying Anion Channels
The FASEB Journal·2025Open Access
Three-year Prognosis of Asthma Phenotypes in Japan
American Journal of Respiratory and Critical Care Medicine·2025
SA4503 Mitigates Adriamycin-Induced Nephropathy via Sigma-1 Receptor in Animal and Cell-Based Models
Pharmaceuticals·2025· 2 citedOpen Access
Shakuyaku-Kanzo-To Prevents Angiotensin Ⅱ-Induced Cardiac Hypertrophy in Neonatal Rat Ventricular Myocytes
Cureus·2024· 2 citedOpen Access
Role of Piezo2 in Schwann Cell Volume Regulation and Its Impact on Neurotrophic Release Regulation
Cellular Physiology and Biochemistry·2024· 10 citedOpen Access
Cardioprotective effects of Moku-boi-to and its impact on AngII-induced cardiomyocyte hypertrophy
Frontiers in Cell and Developmental Biology·2023· 6 citedOpen Access
Cell death induction and protection by activation of ubiquitously expressed anion/cation channels. Part 3: the roles and properties of TRPM2 and TRPM7
Frontiers in Cell and Developmental Biology·2023· 7 citedOpen Access
Intermediate conductance Ca2+-activated potassium channels are activated by functional coupling with stretch-activated nonselective cation channels in cricket myocytes
Frontiers in Insect Science·2023· 1 citedOpen Access
Elucidation of protective mechanism against AngII-induced cardiomyocyte injury by Moku-boi-to
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2023Open Access
Sigma-1 receptor is involved in modification of ER-mitochondria proximity and Ca2+ homeostasis in cardiomyocytes
Journal of Pharmacological Sciences·2022· 23 citedOpen Access
The regulation mechanisms of mitochondrial Ca<sup>2+</sup> signaling mediated by cardiac Sigma-1 receptor
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2022Open Access
Properties, Structures, and Physiological Roles of Three Types of Anion Channels Molecularly Identified in the 2010’s
Frontiers in Physiology·2021· 11 citedOpen Access
Cell Death Induction and Protection by Activation of Ubiquitously Expressed Anion/Cation Channels. Part 2: Functional and Molecular Properties of ASOR/PAC Channels and Their Roles in Cell Volume Dysregulation and Acidotoxic Cell Death
Frontiers in Cell and Developmental Biology·2021· 24 citedOpen Access
TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel
Communications Biology·2021· 17 citedOpen Access
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Frequent Co-authors

Yasuo Mori(25), Yasunobu Okada(21), Kaori Sato(12), Shigeki Kiyonaka(8), Takahiro Shimizu(7), Ryuji Inoue(7), Nobuaki Takahashi(5), Itaru Hamachi(4), Shuji Kaneko(4), Ravshan Z. Sabirov(4), Yoshitsugu Uriu(3), Daisuke Kozai(3), Shinichiro Yamamoto(3), Hiroshi Imahori(3), Tatsuya Murakami(3), Reiko Sakaguchi(3), Kenta Kato(2), Motohiro Nishida(2), Takuro Numaga(2), Yuichi Sawaguchi(2)