Daisuke Kozai

The University of Tokyo — Japan

Neuroscience · Life Sciences

12h-index1.3kcitations21works2.02yr avg
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Research Topics

Ion Channels and Receptors(13), Ion channel regulation and function(5), Phytochemicals and Antioxidant Activities(3), Pain Mechanisms and Treatments(2), Magnesium in Health and Disease(2)

Publications21 total

Cryo-EM structure of human AQP11 reveals a trimeric architecture with a large pore
Science Advances·2026Open Access
Narrowed pore conformations of aquaglyceroporins AQP3 and GlpF
Nature Communications·2025· 4 citedOpen Access
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit
Journal of Molecular Biology·2023· 14 citedOpen Access
The recognition mechanism of the analgesic drug mirogabalin by recombinant human α<sub>2</sub>δ1 protein
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2022Open Access
Recombinant human α<sub>2</sub>δ-1 purification for structural analysis of mirogabalin binding mode
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2021Open Access
Development of a deep learning-based method to identify “good” regions of a cryo-electron microscopy grid
Biophysical Reviews·2020· 34 citedOpen Access
Identification of a prostaglandin D2 metabolite as a neuritogenesis enhancer targeting the TRPV1 ion channel
Scientific Reports·2016· 19 citedOpen Access
Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line
Frontiers in Pharmacology·2016· 27 citedOpen Access
Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels
Current Neuropharmacology·2015· 7 citedOpen Access
TRP Channels: Their Function and Potentiality as Drug Targets
2015· 31 citedOpen Access
Conferring Subtype Selectivity to Modulatory Action of NO on Sensory TRP Channels
Current Neuropharmacology·2014
Transnitrosylation Directs TRPA1 Selectivity in N-Nitrosamine Activators
Molecular Pharmacology·2013· 26 cited
Redox Regulation of Transient Receptor Potential Channels
Antioxidants and Redox Signaling·2013· 153 cited
TRP channels: sensors and transducers of gasotransmitter signals
Frontiers in Physiology·2012· 66 citedOpen Access
TRPA1 underlies a sensing mechanism for O2
Nature Chemical Biology·2011· 265 citedOpen Access
Roles of TRPM2 in oxidative stress
Cell Calcium·2011· 160 cited
Differential Redox Regulation of ORAI Ion Channels: A Mechanism to Tune Cellular Calcium Signaling
Science Signaling·2010· 252 cited
Differential Redox Regulation of ORAI Channels: A Mechanism to Tune T-Cell Responses
Biophysical Journal·2010Open Access
Activation of TRPA1 channels by novel aliphatic N-nitrosamines
2010Open Access
[Structures and variable functions of TRP channels].
PubMed·2009
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Frequent Co-authors

Yasuo Mori(14), Nobuaki Takahashi(10), Kouki Nishikawa(6), Yoshinori Fujiyoshi(6), Shigeki Kiyonaka(4), Tomohiro Numata(4), Reiko Sakaguchi(4), Tomohiko Ohwada(4), Akiko Kamegawa(4), Shinichiro Yamamoto(3), Katsumasa Irie(3), Hiroyuki Hanzawa(3), Kousei Shimada(3), Yutaka Kitano(3), Yusuke Mizuno(2), Ivan Bogeski(2), Carsten Kummerow(2), Dalia Alansary(2), Eva C. Schwarz(2), Richard Koehler(2)