Dario Acampora

Institute of Genetics and Biophysics — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

60h-index12.6kcitations121works23.02yr avg
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Research Topics

Developmental Biology and Gene Regulation(60), Congenital heart defects research(26), Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities(22), Epigenetics and DNA Methylation(16), Genomics and Chromatin Dynamics(15)

Publications120 total

A maternal-effect<i>Padi6</i>variant causes nuclear and cytoplasmic abnormalities in oocytes, as well as failure of epigenetic reprogramming and zygotic genome activation in embryos
Genes & Development·2024· 23 citedOpen Access
A maternal-effect <i>Padi6</i> variant results in abnormal nuclear localization of DNMT1 and failure of epigenetic reprogramming and zygotic genome activation in mouse embryos
2023· 1 citedOpen Access
Direct repression of <i>Nanog</i> and <i>Oct4</i> by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage
Development·2021· 14 citedOpen Access
OTX2 restricts entry to the mouse germline
Nature·2018· 79 citedOpen Access
Full Functional Knockout of Placental Growth Factor by Knockin with an Inactive Variant Able to Heterodimerize with VEGF-A
Cell Reports·2018· 13 citedOpen Access
Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells
Stem Cell Reports·2017· 37 citedOpen Access
Genetic Otx2 mis-localization delays critical period plasticity across brain regions
Molecular Psychiatry·2017· 85 citedOpen Access
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency
Nature Communications·2016· 65 citedOpen Access
Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast
Cell Reports·2016· 72 citedOpen Access
Sox6 and Otx2 Control the Specification of Substantia Nigra and Ventral Tegmental Area Dopamine Neurons
Cell Reports·2014· 145 citedOpen Access
Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex
F1000Research·2014· 10 citedOpen Access
Reorganization of Enhancer Patterns in Transition from Naive to Primed Pluripotency
Cell stem cell·2014· 522 citedOpen Access
Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility
Neuroscience·2014· 17 cited
Quantitative PCR and mass spectrometry data of Otx2 homeoprotein in the mouse visual cortex
Faculty of 1000 Research Ltd·2014Open Access
Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity
Development·2013· 26 citedOpen Access
Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes
Human Molecular Genetics·2013· 45 citedOpen Access
The homeodomain factor <i>Gbx1</i> is required for locomotion and cell specification in the dorsal spinal cord
PeerJ·2013· 7 citedOpen Access
Peer Review #1 of "The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord (v0.3)"
2013Open Access
The transcription factor Otx2 regulates choroid plexus development and function
Development·2013· 132 citedOpen Access
Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition
Development·2012· 196 citedOpen Access
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Frequent Co-authors

Antonio Simeone(49), Virginia Avantaggiato(12), Francesca Tuorto(9), Edoardo Boncinelli(8), Anna Stornaiuolo(7), Maurizio D’Esposito(7), Fulvio Mavilio(6), A. Faiella(6), Maria Pannese(6), Vincenzo Nigro(5), Wolfgang Wurst(5), Massimo Gulisano(4), E. Boncinelli(4), Massimo Signore(4), Eduardo Puelles(4), Daniela Omodei(4), Luca Giovanni Di Giovannantonio(4), Giorgio Corte(4), Philippe Brûlet(3), Paolo Barone(3)