David D. McKemy

University of Southern California — United States

Neuroscience · Life Sciences

33h-index8.8kcitations67works0.72yr avg
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Research Topics

Ion Channels and Receptors(47), Neurobiology and Insect Physiology Research(26), Pain Mechanisms and Treatments(14), Biochemical Analysis and Sensing Techniques(13), Ion channel regulation and function(9)

Publications67 total

Transient Receptor Potential channels (TRP) in GtoPdb v.2025.1
IUPHAR/BPS Guide to Pharmacology CITE·2025· 2 citedOpen Access
The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8
2024Open Access
Opening remarks: What makes TRP channels attractive therapeutic targets?
Elsevier eBooks·2024
Transient Receptor Potential channels (TRP) in GtoPdb v.2023.3
IUPHAR/BPS Guide to Pharmacology CITE·2023· 4 citedOpen Access
Transient Receptor Potential channels (TRP) in GtoPdb v.2023.2
IUPHAR/BPS Guide to Pharmacology CITE·2023· 13 citedOpen Access
TRPM Channels
2023
Transient Receptor Potential channels (TRP) in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE·2023· 3 citedOpen Access
Endogenous Inflammatory Mediators Produced by Injury Activate TRPV1 and TRPA1 Nociceptors to Induce Sexually Dimorphic Cold Pain That Is Dependent on TRPM8 and GFRα3
Journal of Neuroscience·2023· 19 citedOpen Access
Endogenous inflammatory mediators produced by injury activate TRPV1 and TRPA1 nociceptors to induce sexually dimorphic cold pain that is dependent on TRPM8 and GFRα3
2023· 3 citedOpen Access
Immunoglobulin somatic hypermutation in a defined biochemical system recapitulates affinity maturation and permits antibody optimization
Nucleic Acids Research·2022· 5 citedOpen Access
Transient Receptor Potential channels (TRP) in GtoPdb v.2022.1
IUPHAR/BPS Guide to Pharmacology CITE·2022Open Access
Transient receptor potential melastatin 8 is required for nitroglycerin- and calcitonin gene-related peptide–induced migraine-like pain behaviors in mice
Pain·2022· 24 citedOpen Access
Transient Receptor Potential channels (TRP) in GtoPdb v.2021.3
IUPHAR/BPS Guide to Pharmacology CITE·2021· 2 citedOpen Access
Nociceptive afferent phenotyping reveals that transient receptor potential ankyrin 1 promotes cold pain through neurogenic inflammation upstream of the neurotrophic factor receptor GFRα3 and the menthol receptor transient receptor potential melastatin 8
Pain·2020· 19 citedOpen Access
Dominant Role of the Gut Microbiota in Chemotherapy Induced Neuropathic Pain
Scientific Reports·2019· 100 citedOpen Access
Transient Receptor Potential channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
IUPHAR/BPS Guide to Pharmacology CITE·2019· 13 citedOpen Access
Selective cold pain inhibition by targeted block of TRPM8-expressing neurons with quaternary lidocaine derivative QX-314
Communications Biology·2018· 20 citedOpen Access
Molecular basis of peripheral innocuous cold sensitivity
Handbook of clinical neurology·2018· 26 citedOpen Access
Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons
Journal of Investigative Dermatology·2017· 89 citedOpen Access
Cellular permeation of large molecules mediated by TRPM8 channels
Neuroscience Letters·2016· 17 citedOpen Access
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Frequent Co-authors

Wendy Knowlton(8), David Julius(6), Radhika Palkar(5), Daniel D. McCoy(5), Erika K. Lippoldt(4), Yoshio Takashima(4), Richard L. Daniels(4), Shanni Yamaki(4), Serra Ongun(4), Judith A. Airey(4), John L. Sutko(4), Sven‐Eric Jordt(3), Diana M. Bautista(2), Emily R. Liman(2), Nancy A. McNamara(2), Carol Basbaum(2), Angela Sarkisian(2), Thomas J. Deerinck(2), Lucien J. Houenou(2), Anna Ivanenko(2)