Emily R. Liman

Nursing · Health Sciences

39h-index7.6kcitations91works1.32yr avg
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Research Topics

Biochemical Analysis and Sensing Techniques(58), Olfactory and Sensory Function Studies(32), Advanced Chemical Sensor Technologies(27), Ion Channels and Receptors(25), Neurobiology and Insect Physiology Research(23)

Publications91 total

Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface
Nature Communications·2025· 1 citedOpen Access
Epitope Tagging with Genome Editing in Mice Reveals That the Proton Channel OTOP1 Is Apically Localized and Not Restricted to Type III “Sour” Taste Receptor Cells
Journal of Neuroscience·2024· 4 citedOpen Access
Activation of the proton channel OTOP1 by ammonium chloride as a mechanism for taste transduction
Biophysical Journal·2024Open Access
Epitope Tagging via CRISPR/Cas9 Reveals the Apical Localization of the Sour Receptor OTOP1 in Taste Cells
SSRN Electronic Journal·2024Open Access
The proton channel OTOP1 is a sensor for the taste of ammonium chloride
Nature Communications·2023· 46 citedOpen Access
Proton Channels
2023· 1 cited
Zinc activation of OTOP proton channels identifies structural elements of the gating apparatus
eLife·2023· 14 citedOpen Access
Author response: Zinc activation of OTOP proton channels identifies structural elements of the gating apparatus
2023Open Access
Small molecule discovery for modulation of Otopetrin proton channels
Biophysical Journal·2023· 1 cited
Subtype-specific potentiation of otopetrin proton channels by Zn2+ and its structural basis
Biophysical Journal·2023Open Access
Zn <sup>2+</sup> potentiation of OTOP proton channels identifies structural elements of the gating apparatus
2022Open Access
Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels
eLife·2022· 31 citedOpen Access
Author response: Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels
2022Open Access
Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels
2022Open Access
The evolution of sour taste
Proceedings of the Royal Society B Biological Sciences·2022· 36 citedOpen Access
Subtype-specific gating mechanisms of OTOP channels by protons
Biophysical Journal·2022
Requirement for an Otopetrin-like protein for acid taste in <i>Drosophila</i>
Proceedings of the National Academy of Sciences·2021· 43 citedOpen Access
The Cellular and Molecular Basis of Sour Taste
Annual Review of Physiology·2021· 28 citedOpen Access
Insights into a receptor that lets insects sense scents
Nature·2021· 1 cited
Requirement for an Otopetrin-Like protein for acid taste in <i>Drosophila</i>
2021· 1 citedOpen Access
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Frequent Co-authors

Yu-Hsiang Tu(6), Bochuan Teng(6), Rui B. Chang(6), Wenlei Ye(4), Sue C. Kinnamon(4), Peter Hess(3), Alexander J. Cooper(3), Heather N. Turner(3), Yuanyuan Y. Wang(3), Hang Waters(3), Zheng Zhang(3), Courtney Wilson(3), Joshua P. Kaplan(3), Ziyu Liang(3), Craig Montell(2), David P. Corey(2), Dan Liu(2), Don B. Arnold(2), Eric M. Mulhall(2), David D. McKemy(2)