Ichiro Azuma

The University of Tokyo — Japan

Chemistry · Physical Sciences

54h-index11.3kcitations440works0.02yr avg
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Research Topics

Carbohydrate Chemistry and Synthesis(68), Glycosylation and Glycoproteins Research(45), Immune Response and Inflammation(43), Mycobacterium research and diagnosis(38), Cancer Research and Treatments(35)

Publications440 total

P03-12 Network-Based Modeling of Immune Cell Interactions to Elucidate the Mechanisms of Toxicity
Toxicology Letters·2025
Immune adjuvant therapy using Bacillus Calmette–Guérin cell wall skeleton (BCG-CWS) in advanced malignancies
Medicine·2019· 37 citedOpen Access
Stimulation with Synthetic Acyl-MDP Derivatives of Host-Defense Mechanism against Cancer and Viral Infections
2015
Vaccination with WT-1 (Wilms’ Tumor gene-1) peptide and BCG-CWS in melanoma
European Journal of Dermatology·2012· 11 cited
Zinc suppresses Th17 development via inhibition of STAT3 activation
International Immunology·2010· 171 cited
Bacillus Calmette‐Guérin cell‐wall skeleton enhances the killing activity of cytotoxic lymphocyte‐activated human dendritic cells transduced with the prostate‐specific antigen gene
British Journal of Urology·2009· 3 cited
Injection of cell-wall skeleton of Mycobacterium bovis BCG draining to a sentinel lymph node eliminates both lymph node metastases and the primary transplanted tumor.
PubMed·2008· 2 cited
Immune response against cell-wall skeleton of Mycobacterium bovis BCG at the inoculation site and peripheral lymphoid organs.
PubMed·2008· 2 cited
Efficient Syntheses of a Series of Trehalose Dimycolate (TDM)/Trehalose Dicorynomycolate (TDCM) Analogues and Their Interleukin-6 Level Enhancement Activity in Mice Sera
The Journal of Organic Chemistry·2007· 36 cited
Enhancement of Immunologic Tumor Regression by Intratumoral Administration of Dendritic Cells in Combination with Cryoablative Tumor Pretreatment and Bacillus Calmette-Guerin Cell Wall Skeleton Stimulation
Clinical Cancer Research·2006· 87 cited
18 Systematic Synthesis of Trehalose Dicorynomycolate (TDCM) Analogues and Their IL-6 Level Enhancement Activity
天然有機化合物討論会講演要旨集·2006
Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation
The Journal of Immunology·2005· 95 citedOpen Access
WT1 peptide vaccination combined with BCG-CWS is more efficient for tumor eradication than WT1 peptide vaccination alone
Cancer Immunology Immunotherapy·2004· 43 citedOpen Access
<i>Mycobacterium bovis</i>BCG Cell Wall-Specific Differentially Expressed Genes Identified by Differential Display and cDNA Subtraction in Human Macrophages
Infection and Immunity·2004· 81 citedOpen Access
Adjuvant-Mediated Tumor Regression and Tumor-Specific Cytotoxic Response Are Impaired in MyD88-Deficient Mice
Cancer Research·2004· 105 cited
Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer.
PubMed·2004· 106 cited
Simultaneous Blocking of Human Toll-Like Receptors 2 and 4 Suppresses Myeloid Dendritic Cell Activation Induced by<i>Mycobacterium bovis</i>Bacillus Calmette-Guerin Peptidoglycan
Infection and Immunity·2003· 157 citedOpen Access
Erythrocyte-Replaced Mouse Model for Haemoparasite Studies: Comparison of NOD/shi-scid and C.B-17/Jcl-scid Mouse upon Acceptability of Human Erythrocytes
Journal of Veterinary Medical Science·2003· 3 citedOpen Access
Inhibitory effect of BCG cell-wall skeletons (BCG-CWS) emulsified in squalane on tumor growth and metastasis in mice
Archives of Pharmacal Research·2002· 15 cited
Structural–functional relationship of pathogen-associated molecular patterns: lessons from BCG cell wall skeleton and mycoplasma lipoprotein M161Ag
Microbes and Infection·2002· 16 cited
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Frequent Co-authors

Yuichi Yamamura(8), Seiichi Tokura(7), Misako Matsumoto(6), Kumao Toyoshima(6), Tsukasa Seya(6), Norio Nishi(6), Keiko Nishimura(5), Yung–Choon Yoo(5), Ikuo Saiki(5), Shizuo Akira(4), I Saiki(4), Thomas J. Meyer(4), Kei–ichi Shimazaki(4), Takashi Akazawa(4), Hideji Fujii(3), Fuminori Abe(3), Edgar Ribi(3), Berton Zbar(3), Ryosuke Watanabe(3), Chiaki Ishihara(3)