Kumao Toyoshima

RIKEN Center for Integrative Medical Sciences — Japan

Agricultural and Biological Sciences · Life Sciences

45h-index11.8kcitations139works0.02yr avg
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Research Topics

Animal Virus Infections Studies(23), Virus-based gene therapy research(21), HER2/EGFR in Cancer Research(18), Monoclonal and Polyclonal Antibodies Research(17), Immune Response and Inflammation(15)

Publications139 total

Innate immune therapy with a Bacillus Calmette-Guérin cell wall skeleton after radical surgery for non-small cell lung cancer: A case-control study
Surgery Today·2009· 34 cited
Protein Tyrosine Kinases Belonging to the <i>src</i> Family
Novartis Foundation symposium·2007· 7 cited
Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation
The Journal of Immunology·2005· 95 citedOpen Access
<i>Mycobacterium bovis</i>BCG Cell Wall-Specific Differentially Expressed Genes Identified by Differential Display and cDNA Subtraction in Human Macrophages
Infection and Immunity·2004· 81 citedOpen Access
Adjuvant-Mediated Tumor Regression and Tumor-Specific Cytotoxic Response Are Impaired in MyD88-Deficient Mice
Cancer Research·2004· 105 cited
Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer.
PubMed·2004· 106 cited
Simultaneous Blocking of Human Toll-Like Receptors 2 and 4 Suppresses Myeloid Dendritic Cell Activation Induced by<i>Mycobacterium bovis</i>Bacillus Calmette-Guerin Peptidoglycan
Infection and Immunity·2003· 157 citedOpen Access
Mycobacterium bovis BCG Cell Wall and Lipopolysaccharide Induce a Novel Gene, BIGM103, Encoding a 7-TM Protein: Identification of a New Protein Family Having Zn-Transporter and Zn-Metalloprotease Signatures
Genomics·2002· 147 cited
Structural–functional relationship of pathogen-associated molecular patterns: lessons from BCG cell wall skeleton and mycoplasma lipoprotein M161Ag
Microbes and Infection·2002· 16 cited
Molecular assembly of CD46 with CD9, alpha3–beta1 integrin and protein tyrosine phosphatase SHP-1 in human macrophages through differentiation by GM-CSF
Molecular Immunology·2002· 34 cited
Innate Immune Therapy For Cancer
Advances in experimental medicine and biology·2002· 11 cited
High serum levels of additional IL-18 forms may be reciprocally correlated with IgE levels in patients with atopic dermatitis
Immunology Letters·2001· 21 cited
Molecular Cloning and Functional Characterization of Chicken Toll-like Receptors
Journal of Biological Chemistry·2001· 178 citedOpen Access
Protein polymorphism of human IL-18 identified by monoclonal antibodies
International Journal of Molecular Medicine·2001· 4 cited
Molecular cloning and functional characterization of guinea pig IL-12
International Immunology·2001· 24 cited
Distribution of IL-18 and IL-18 receptor in human skin: various forms of IL-18 are produced in keratinocytes
Archives of Dermatological Research·2001· 44 cited
An Alternative Form of IL-18 in Human Blood Plasma: Complex Formation with IgM Defined by Monoclonal Antibodies
The Journal of Immunology·2001· 14 citedOpen Access
Mycobacterium bovis Bacillus Calmette-Guerin and Its Cell Wall Complex Induce a Novel Lysosomal Membrane Protein, SIMPLE, That Bridges the Missing Link between Lipopolysaccharide and p53-inducible Gene, LITAF(PIG7), and Estrogen-inducible Gene, EET-1
Journal of Biological Chemistry·2001· 102 citedOpen Access
Human Intelectin Is a Novel Soluble Lectin That Recognizes Galactofuranose in Carbohydrate Chains of Bacterial Cell Wall
Journal of Biological Chemistry·2001· 366 citedOpen Access
Human Macrophages Produce Dimeric Forms of IL-18 Which Can Be Detected with Monoclonal Antibodies Specific for Inactive IL-18
Biochemical and Biophysical Research Communications·2001· 11 cited
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Frequent Co-authors

Tetsu Akiyama(17), Misako Matsumoto(12), Tadashi Yamamoto(11), Tsukasa Seya(11), Akihiko Matsumine(6), Ichiro Azuma(6), Kentaro Semba(5), Tadashi Yamamoto(5), Shizuo Akira(5), Yuji Yamanashi(4), Shoutaro Tsuji(4), Junji Uehori(4), Peter K. Vogt(4), Takashi Akazawa(4), Nasim A. Begum(4), Nobuyuki Miyajima(3), Osamu Takeuchi(3), Sadaaki Kawai(3), Fumihiko Hamada(3), Takao Ishidate(3)