Bo F. Hansen

Novo Nordisk (Denmark) — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index3.3kcitations57works20.52yr avg
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Research Topics

Metabolism, Diabetes, and Cancer(33), Pancreatic function and diabetes(21), Adipose Tissue and Metabolism(15), Growth Hormone and Insulin-like Growth Factors(10), Muscle metabolism and nutrition(9)

Publications56 total

Functionally Mature Bioengineered Human Skeletal Muscle Tissues Capture Essential Aspects of Glucose Metabolism
2026Open Access
Glucose-sensitive insulin with attenuation of hypoglycaemia
Nature·2024· 41 citedOpen Access
Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models
Diabetologia·2022· 1 citedOpen Access
Author Correction: Molecular engineering of safe and efficacious oral basal insulin
Nature Communications·2020· 1 citedOpen Access
Molecular engineering of safe and efficacious oral basal insulin
Nature Communications·2020· 56 citedOpen Access
236-OR: Molecular and Biological Properties of Insulin Icodec, a New Insulin Analog Designed to Give a Long Half-Life Suitable for Once-Weekly Dosing
Diabetes·2020· 23 cited
Increased insulin receptor binding and increased IGF-1 receptor binding are linked with increased growth of L6hIR cell xenografts in vivo
Scientific Reports·2020· 7 citedOpen Access
Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine
Journal of Diabetes Science and Technology·2019Open Access
Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor
Journal of Immunological Methods·2018· 7 citedOpen Access
Activation of insulin receptors and IGF-1 receptors in COLO-205 colon cancer xenografts by insulin and insulin analogue X10 does not enhance growth under normo- or hypoglycaemic conditions
Diabetologia·2018· 6 citedOpen Access
A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome
Diabetes·2018· 38 citedOpen Access
Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors
Endocrinology·2017· 7 citedOpen Access
Elucidating the Biological Roles of Insulin and Its Receptor in Murine Intestinal Growth and Function
Endocrinology·2017· 9 citedOpen Access
A framework for the<i>in vitro</i>evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues
Carcinogenesis·2015· 16 citedOpen Access
Surface‐expressed insulin receptors as well as IGF‐I receptors both contribute to the mitogenic effects of human insulin and its analogues
Journal of Applied Toxicology·2014· 15 cited
Treatment with Insulin Analog X10 and IGF-1 Increases Growth of Colon Cancer Allografts
PLoS ONE·2013· 36 citedOpen Access
Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH<sub>2</sub>-terminal (sites 2 + 2a) phosphorylation
American Journal of Physiology-Endocrinology and Metabolism·2013· 22 citedOpen Access
Agonism and Antagonism at the Insulin Receptor
PLoS ONE·2012· 51 citedOpen Access
Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway
Endocrine Related Cancer·2012· 9 citedOpen Access
Molecular Characterisation of Long-Acting Insulin Analogues in Comparison with Human Insulin, IGF-1 and Insulin X10
PLoS ONE·2012· 42 citedOpen Access
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Frequent Co-authors

Jørgen F. P. Wojtaszewski(14), Erik A. Richter(14), Henning Hvid(8), Erica Nishimura(7), Grith Skytte Olsen(6), Henning Beck‐Nielsen(6), Tine Glendorf(6), Anne Lützen(6), Bente Kiens(5), Jesper B. Birk(5), Carsten E. Stidsen(5), Rita Slaaby(5), Jakob N. Nielsen(4), D. Grahame Hardie(4), Kurt Højlund(4), Christian L. Brand(4), Thomas Kjeldsen(4), Thomas Åskov Pedersen(4), Martin B. Oleksiewicz(4), Anne Charlotte Hegelund(4)